ArticlePloS one2026
Evaluation of replication success: A statistical perspective and extended analysis of the SCORE data.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Replications are more and more conducted in multiple research fields. A recent large-scale replication project, Systematizing Confidence in Open Research and Evidence (SCORE) project, replicated 274 effects from research on business, economics, education, political science, psychology, and sociology. An open question remains how replication success can best be assessed. Thirteen methods for assessing replication success were applied in the SCORE project. The first goal of this paper is studying the statistical properties of replication success methods by a numerical study tailored to the characteristics of the SCORE data. The results of the numerical study show that replication success methods are unable to reliably draw a conclusion about replication success for typical sample sizes of the original study and replication. Hence, there is often insufficient information in one original study and one replication for drawing definite conclusions. The second goal of this paper is taking a novel perspective on the SCORE data by estimating the effect size of an original study and replication. Estimators based on meta-analysis methods that correct for potential bias in the original study were close to unbiased when synthesizing the original study and replication. The reanalysis of the SCORE data revealed that meta-analytic estimates were substantially closer to the effect size of the replication compared to the original study. The null hypothesis of no effect was rejected by the meta-analysis methods in 59.2% to 81.3% of the pairs of an original study and replication. We recommend researchers to make sure that methods for analyzing replicability have favorable statistical properties for the data at hand before applying these methods.
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