Evidence map›Paper›PMID 42814888›Full record

ArticleChemistry & biodiversity2026

Exploring the Neuropharmacological Potential of Ligustrum sinense Relevant to Parkinson's Disease: In Vivo and In Silico Study.

Sowmitro Das, S M Istiaque Hamim, Md Nazmul Hasan Zilani, Kazi Sneha Chhando, Puza Das, Md Ridoy Hossain, Md Imtiaz, Jebin Tasmin, Roney Miah, Md Nazmul Hasan

Abstract read
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In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sowmitro Das *Laboratory of Pharmaceutical Biotechnology & Bioinformatics, Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore, Bangladesh.ORCID https://orcid.org/0009-0003-9119-5017
S M Istiaque Hamim *Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, Kuantan, Pahang, Malaysia.ORCID https://orcid.org/0009-0008-4393-7692
Md Nazmul Hasan ZilaniDepartment of Pharmacy, Jashore University of Science and Technology, Jashore, Bangladesh.ORCID https://orcid.org/0000-0002-5339-6665
Kazi Sneha ChhandoFaculty of Industrial Sciences and Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, Kuantan, Pahang, Malaysia.
Puza DasDepartment of Zoology, Government Brajalal College, Khulna, Bangladesh.
Md Ridoy HossainLaboratory of Pharmaceutical Biotechnology & Bioinformatics, Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore, Bangladesh.
Md ImtiazLaboratory of Pharmaceutical Biotechnology & Bioinformatics, Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore, Bangladesh.ORCID https://orcid.org/0009-0006-5775-2010
Jebin TasminFaculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.ORCID https://orcid.org/0009-0001-8255-4335
Roney MiahFaculty of Industrial Sciences and Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, Kuantan, Pahang, Malaysia.ORCID https://orcid.org/0000-0003-2512-0837
Md Nazmul HasanLaboratory of Pharmaceutical Biotechnology & Bioinformatics, Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore, Bangladesh.ORCID https://orcid.org/0000-0002-9122-1129

Funding

Ministry of Posts, Telecommunications and Information Technology, Department of Information and Communication Technology, Bangladesh ID: 22-40Ministry of Science and Technology, Bangladesh MoST/2021-22/BS-277
6 · The paper itself

Abstract

Medicinal plants are valuable sources of bioactive compounds with potential applications in neurodegenerative disorders. This study investigated the antioxidant, neuropharmacological, and monoamine oxidase (MAO) inhibitory activities of Ligustrum sinense (L. sinense) leaf extract through in vitro, in vivo, and in silico approaches. Antioxidant activity assessed by the DPPH assay demonstrated moderate free radical scavenging capacity (IC

Indexed as

AntioxidantsLigustrumMonoamine Oxidase InhibitorsParkinson DiseasePlant ExtractsAnimalsBehavior, AnimalComputer SimulationDose-Response Relationship, DrugMaleMiceMolecular Docking SimulationMolecular Dynamics SimulationMonoamine OxidasePlant LeavesRatsAntioxidantsMonoamine OxidaseMonoamine Oxidase InhibitorsPlant Extractsantioxidant activityin silicoin vivoLigustrum sinenseMAO‐A and MAO‐Bneuropharmacological activityParkinson's disease

Identifiers

PMID42814888
PMCPMC13626602

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.