Evidence map›Paper›PMID 42816435›Full record

ArticleHuman brain mapping2026

Unveiling Functional-Metabolic Synergy in the Healthy Brain: Multivariate Integration of Dynamic [

Claudia Tarricone, Giulia Vallini, Giorgia Baron, Massimiliano Facca, Erica Silvestri, Tommaso Volpi, Andrei G Vlassenko, Manu S Goyal, Alessandra Bertoldo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human brain mapping, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Claudia TarriconeDepartment of Information Engineering, University of Padova, Padova, Italy.ORCID https://orcid.org/0009-0008-1767-5473
Giulia ValliniDepartment of Information Engineering, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-9634-8401
Giorgia BaronDepartment of Information Engineering, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-0866-4982
Massimiliano FaccaDepartment of Information Engineering, University of Padova, Padova, Italy.
Erica SilvestriDepartment of Information Engineering, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-1853-0777
Tommaso VolpiPadova Neuroscience Center, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-5451-6710
Andrei G VlassenkoNeuroimaging Laboratories at the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USA.ORCID https://orcid.org/0000-0002-4776-4855
Manu S GoyalNeuroimaging Laboratories at the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USA.ORCID https://orcid.org/0000-0003-1970-4270
Alessandra BertoldoDepartment of Information Engineering, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-6262-6354

Funding

Aerobic Glycolysis in the Development ofAlzheimer's DiseaseR01AG053503 · NIA · WASHINGTON UNIVERSITY · PI RAICHLE, MARCUS E, VLASSENKO, ANDREI G. · 2017 to 2021
$4.1M
Aerobic Glycolysis: A Marker of BrainResilience to Aging and Alzheimer's DiseaseR01AG057536 · NIA · WASHINGTON UNIVERSITY · PI GOYAL, MANU S, VLASSENKO, ANDREI G. · 2017 to 2021
$3.7M
Ministero dell'Università e della Ricerca DN. 1553 11.10.2022National Recovery and Resilience PlanNIA NIH HHS R01 AG053503NIA NIH HHS R01 AG057536project MNESYS
6 · The paper itself

Abstract

Despite accounting for only 2% of body weight, the human brain requires significant amounts of glucose, even at rest, underscoring the importance of functional-metabolic relationships. Previous studies revealed moderate associations between resting-state fMRI functional connectivity (FC) and local metabolism via [

Indexed as

BrainConnectomeGlucoseMagnetic Resonance ImagingNerve NetPositron-Emission TomographyAdultFemaleFluorodeoxyglucose F18HumansMaleMultimodal ImagingRadiopharmaceuticalsFluorodeoxyglucose F18GlucoseRadiopharmaceuticalsBOLD frequency bandsdynamic [18F]FDG‐PETfunctional‐metabolic integrationhemodynamicspartial least squares correlation

Identifiers

PMID42816435
PMCPMC13626976

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.