Evidence map›Paper›PMID 42818154›Full record

ArticlebioRxiv : the preprint server for biology2026

An NR2F1-dependent retinoic acid network controls retinal specialization in mice and reveals foveal hypoplasia in patients with BBSOAS.

Paolo Piovani, Carole Belliardo, Rahul Makam, Boglarka Zambo, Annabelle Mantilleri, Amandine Chassot, Gergo Gogl, Christian P Schaaf, Seth Blackshaw, Patrick Yu-Wai-Man and 2 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Paolo PiovaniUniversité Côte d'Azur, CNRS, Inserm, iBV, Nice, France.ORCID 0009-0004-7694-7687
Carole BelliardoMaison de la Modélisation, de la Simulation et des Interactions (MSI), Université Côte d'Azur, Nice, France.ORCID 0000-0002-8677-1783
Rahul MakamMoorfields Eye Hospital NHS Foundation Trust, London, UK.ORCID 0000-0002-9077-8945
Boglarka ZamboUniversité Côte d'Azur, CNRS, Inserm, iBV, Nice, France.
Annabelle MantilleriUniversité Côte d'Azur, CNRS, Inserm, iBV, Nice, France.ORCID 0009-0006-5015-4122
Amandine ChassotUniversité Côte d'Azur, CNRS, Inserm, iBV, Nice, France.ORCID 0000-0003-1242-9456
Gergo GoglUniversité Côte d'Azur, CNRS, Inserm, iBV, Nice, France.ORCID 0000-0002-8597-3711
Christian P SchaafInstitute of Human Genetics, Heidelberg University, Heidelberg, Germany.ORCID 0000-0002-2148-7490
Seth BlackshawSolomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-1338-8476
Patrick Yu-Wai-ManMoorfields Eye Hospital NHS Foundation Trust, London, UK.ORCID 0000-0001-7847-9320
Michele BertacchiUniversité Côte d'Azur, CNRS, Inserm, iBV, Nice, France.ORCID 0000-0002-4402-4974
Michèle StuderUniversité Côte d'Azur, CNRS, Inserm, iBV, Nice, France.ORCID 0000-0001-7105-2957

Funding

Identification of gene regulatory networks controlling temporal patterning in retinal progenitor cells and neurogenic Müller gliaR01EY036173 · NEI · JOHNS HOPKINS UNIVERSITY · PI Seth Blackshaw · 2024 to 2026
$2.0M
NEI NIH HHS R01 EY036173
6 · The paper itself

Abstract

The molecular programs that establish specialized retinal regions during development are essential for high-acuity vision, yet how their disruption contributes to human visual disorders remains poorly understood. Bosch-Boonstra-Schaaf optic atrophy syndrome (BBSOAS), caused by pathogenic variants in

Identifiers

PMID42818154
PMCPMC13622096

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.