Evidence map›Paper›PMID 42818374›Full record

ArticlebioRxiv : the preprint server for biology2026

Network-specific metabolic cost of functional connectivity in the human brain.

Sarah M Tüchler, Pia Falb, Christian Milz, Matej Murgaš, Murray B Reed, Samantha Graf, Gabriel Schlosser, Clemens Schmidt, Alexandra Mayerweg, Sebastian Klug and 13 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Sarah M TüchlerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0009-0005-2458-0972
Pia FalbDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0000-0003-4817-3499
Christian MilzDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0000-0002-1347-0744
Matej MurgašDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0000-0001-7643-2182
Murray B ReedDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0000-0002-4873-608X
Samantha GrafDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0009-0003-8502-9389
Gabriel SchlosserDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0009-0001-0183-1100
Clemens SchmidtDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0000-0003-3138-6869
Alexandra MayerwegDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0009-0004-5444-8190
Sebastian KlugDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0000-0001-8714-6608
Ivan PörnbacherDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0009-0007-4180-125X
Lukas ArtmeierDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0009-0000-4788-2440
Adam HarouakDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0009-0002-3592-2446
Aurelia SahlDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0009-0000-2712-3607
Maximilian GrohmannDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0009-0008-8075-2507
Lukas NicsDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Austria.ORCID 0000-0002-1034-876X
Godber M GodbersenDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0000-0002-9739-0724
Sazan RasulDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Austria.ORCID 0000-0003-2898-3232
Dan RujescuDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0000-0002-1432-313X
Marcus HackerDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Austria.ORCID 0000-0002-4222-4083
Rupert LanzenbergerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0000-0003-4641-9539
Andreas HahnDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.ORCID 0000-0001-9727-7580
Alzheimer's Disease Neuroimaging Initiative

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite decades of extensive research, the complex architecture underlying human brain signaling remains incompletely understood. Previous work investigating the relationship between brain glucose metabolism and functional connectivity (FC) employed whole-brain analysis, without accounting for network interactions, dependencies or hierarchies. Here, we assess network-specific differences in the relationship between FC and metabolic demand, using [

Indexed as

functional connectivityglucose metabolismnetwork architecture

Identifiers

PMID42818374
PMCPMC13622659

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.