Evidence map›Paper›PMID 42818819›Full record

ArticlebioRxiv : the preprint server for biology2026

A Full Spectrum Fibroblast Profiling Panel Reveals Phenotypic and Metabolic Heterogeneity of Cancer-Associated Fibroblasts at the Single-Cell Level.

Kevin Muñoz Forti, Marta Storl-Desmond, Sayana E Isaac, Daniel Martínez, Michał Nizio, Shan Lin, Aniruddhsingh Solanki, Simon Schw Rer

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kevin Muñoz FortiSection of Hematology/Oncology, Department of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-9473-6419
Marta Storl-DesmondSection of Hematology/Oncology, Department of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-2312-0289
Sayana E IsaacSection of Hematology/Oncology, Department of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL 60637, USA.ORCID 0009-0003-2910-0451
Daniel MartínezSection of Hematology/Oncology, Department of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL 60637, USA.
Michał NizioSection of Hematology/Oncology, Department of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL 60637, USA.ORCID 0009-0005-1703-1545
Shan LinSection of Hematology/Oncology, Department of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL 60637, USA.
Aniruddhsingh SolankiAnimal Resources Center, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-7190-7852
Simon Schw RerSection of Hematology/Oncology, Department of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-2972-9917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer-associated fibroblasts (CAFs) exhibit extensive transcriptional and phenotypic heterogeneity and are highly plastic. Routine approaches to resolving CAF heterogeneity at the single-cell and protein levels are lacking, making it difficult to assess changes in CAF state in response to perturbations. Here, we present an optimized 28-marker spectral flow cytometry panel that uses unsupervised clustering to resolve CAF states across

Identifiers

PMID42818819
PMCPMC13622700

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.