ArticleHealth science reports2026
Association of Serum Vitamin D Level and Hematological Inflammatory Indices in Participants of the MASHAD Study.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
11 authors.
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Abstract
Background and Aim: Vitamin D, a fat-soluble vitamin, has various vital roles in physiological processes. Recent evidence suggests that optimal vitamin D levels may be associated with improved immune function and reduced systemic inflammation. The present study aims to evaluate associations between serum vitamin D levels and various hematological inflammatory indices in participants of the MASHAD cohort study, Mashhad, Iran. Methods: This study was designed as a cross-sectional analysis conducted within the framework of phase I of the MASHAD cohort study. Participants (aged ≥ 18 years old and signed an informed consent) were recruited from a defined population, ensuring the representativeness of the sample for evaluation of potential association between serum vitamin D levels and hematological inflammatory indices including Red Cell Distribution Width (RDW-CV), high-sensitivity C-reactive protein (hs-CRP), systemic immune-inflammation index (SII), platelet-to-lymphocyte ratio (PLR), Neutrophil-to-Lymphocyte Ratio (NLR), Mean Platelet Volume (MPV), and Platelet Distribution Width (PDW). Results: A total of 458 participants were included in the current study, comprising 229 males and 229 females. Serum vitamin D had weak correlation with hs-CRP ( Conclusion: The current findings revealed a weak association between serum vitamin D concentrations and inflammatory indicators. Among hematological parameters, gender-based differences were observed, with PDW and RDW levels significantly varying between vitamin D quartiles in women.
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