ArticleACS omega2026
Surface-Engineered Magnesium Metal-Organic Frameworks for Curcumin Stabilization: Interfacial Coordination Enhances Aqueous Stability and Boosts Antioxidant Efficacy 32-Fold.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Curcumin possesses exceptional therapeutic and antioxidant potential, yet its clinical translation remains severely bottlenecked by rapid hydrolytic degradation and poor stability in aqueous environments. Herein, we report a robust and highly efficient magnesium-based metal-organic framework (MgMOF) platform designed to encapsulate and stabilize curcumin via a facile wet impregnation strategy. Systematic optimization of processing parametersincluding kinetics, thermodynamics, and mass ratiosrevealed that a 1 h stirring regime with a 1:4 MgMOF-to-curcumin molar ratio yields a superior loading capacity of 46 wt % while preserving the long-range crystalline order of the host framework. Comprehensive structural and physiochemical characterization utilizing thermogravimetric analysis, powder X-ray diffraction, scanning electron microscopy, and Fourier-transform infrared spectroscopy confirmed successful surface adsorption driven by specific coordination interactions between the curcumin functional groups and the open Mg
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Registered trials
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