Evidence map›Paper›PMID 42823399›Full record

ReviewThe pharmacogenomics journal2026

The role of pharmacogenomics in epilepsy treatment: advancements in personalized medicine.

Najmeh Ahangari, Mohammad Doosti, Mojtaba Safi, Narges Hashemi, Shima Imannezhad, Bita Barazandeh, Ehsan Ghayoor Karimiani, Mehran Beiraghi Toosi

Abstract readReview
PubMed Publisher
In one paragraph

Review in The pharmacogenomics journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Najmeh AhangariDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID http://orcid.org/0000-0001-7091-3188
Mohammad DoostiDepartment of Medical Genetics, Next Generation Genetic Polyclinic, Mashhad, Iran.ORCID http://orcid.org/0000-0002-2728-8265
Mojtaba SafiDepartment of Medical Genetics, Next Generation Genetic Polyclinic, Mashhad, Iran.ORCID http://orcid.org/0000-0002-0317-7392
Narges HashemiDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID http://orcid.org/0000-0002-1767-7873
Shima ImannezhadDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID http://orcid.org/0000-0002-5537-2763
Bita BarazandehDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID http://orcid.org/0009-0009-0751-7866
Ehsan Ghayoor KarimianiDepartment of Medical Genetics, Next Generation Genetic Polyclinic, Mashhad, Iran. eghayoor@gmail.com.ORCID http://orcid.org/0000-0003-3858-7073
Mehran Beiraghi ToosiDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. beiraghitm1@gmail.com.ORCID http://orcid.org/0000-0002-0569-1117

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilepsy is a diverse and often severe neurological disorder characterized by frequent and unpredictable seizures caused by the simultaneous discharge of brain cells in one or both hemispheres. Recently, there has been a significant shift in the approach to healthcare, moving from a standardized model to a more personalized and targeted model. This transformation has been made possible by advances in pharmacogenomics. It has great potential in customizing treatments based on the specific needs of patients, and this is particularly evident in the management of epilepsy. With ongoing research, the development of comprehensive genetic databases, and the integration of pharmacogenomics into clinical practice using artificial intelligence, a brighter future can be expected for personalized epilepsy treatment. Using the potential of pharmacogenomics, we can expect to provide the best possible care for epilepsy patients and improve their quality of life.

Indexed as

AnticonvulsantsEpilepsyPharmacogeneticsPrecision MedicineHumansQuality of LifeAnticonvulsants

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.