ArticleNature communications2026
SLC4A7/NBCn1 maintains intracellular pH to support mTORC1 activity and antibody-secreting cell differentiation.
Ke Hu, Yin-Hu Wang, Anthony Y Tao, Maxwell McDermott, Miki Jishage, Li Zhong, Thomas Boehringer, Marcus J Hines, Sergei B Koralov, Ebbe Boedtkjer and 1 more
Abstract read
In one paragraphArticle in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
11 authors.
Ke Hu *Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Yin-Hu Wang *Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-3637-8852 Anthony Y Tao *Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Maxwell McDermottDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Miki JishageDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Li ZhongDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Thomas BoehringerDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-4289-7931 Marcus J HinesDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Sergei B KoralovDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-4843-3791 Stefan FeskeDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA. stefan.feske@nyulangone.org.ORCID 0000-0001-5431-8178 Funding
CRAC Channel Deficiency in Immunity to InfectionR01AI097302 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2012 to 2022
$5.6MIon channels regulating plasma cell differentiation and humoral immunityR01AI175276 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI STEFAN FESKE · 2024 to 2026
$2.0MNIAID NIH HHS R01 AI097302NIAID NIH HHS R01 AI175276U.S. Department of Health & Human Services | National Institutes of Health (NIH) AI097302U.S. Department of Health & Human Services | National Institutes of Health (NIH) AI175276
6 · The paper itselfAbstract
Antibody-producing plasmablasts (PB) and plasma cells (PC) are critical for humoral immunity, autoimmunity and vaccine responses. Despite the importance of environmental stressors in regulating humoral immune responses, the influence of pH on PB and PC differentiation remains elusive. Here, we identify SLC4A7/NBCn1, a Na
Indexed as
Antibody-Producing CellsCell DifferentiationMechanistic Target of Rapamycin Complex 1Sodium-Bicarbonate SymportersAnimalsAntibody FormationB-LymphocytesHydrogen-Ion ConcentrationImmunity, HumoralInfluenza A virusMiceMice, Inbred C57BLMice, KnockoutPlasma CellsMechanistic Target of Rapamycin Complex 1Sodium-Bicarbonate Symporters
Identifiers
PMID42823451
PMCPMC13631254
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