Evidence map›Paper›PMID 42824179›Full record

Trial reportFrontiers in nutrition2026

Gut health and microbiome modulation by the heat-killed postbiotic beLP1

Ranjith Kumar Manoharan, Kwon-Il Han, Yura Lee, Sunhwa Baek, Eunjung Moon, Youn Bum Park, Junhui Cho, Jayesh Chaudhary, Hyun-Dong Shin

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05820737 (A Randomized, Double Blind, Placebo Controlled, Parallel Group Study to Assess the Gut Health Effects of Heat-killed Post-biotics EF2001 & beLP1 in Overweight and Obese Adults), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05820737 nacompletednot on this map

A Randomized, Double Blind, Placebo Controlled, Parallel Group Study to Assess the Gut Health Effects of Heat-killed Post-biotics EF2001 & beLP1 in Overweight and Obese Adults

TypeinterventionalSponsorVedic Lifesciences Pvt. Ltd.Ran2024 to 2025Enrolled155ConditionsGastrointestinal DysfunctionArmsEF2001, beLP1, Placebo
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ranjith Kumar ManoharanResearch & Development Center, Bereum Co., Ltd., Wonju, Republic of Korea.
Kwon-Il HanResearch & Development Center, Bereum Co., Ltd., Wonju, Republic of Korea.
Yura LeeResearch & Development Center, Bereum Co., Ltd., Wonju, Republic of Korea.
Sunhwa BaekResearch & Development Center, Bereum Co., Ltd., Wonju, Republic of Korea.
Eunjung MoonResearch & Development Center, Bereum Co., Ltd., Wonju, Republic of Korea.
Youn Bum ParkResearch & Development Center, Bereum Co., Ltd., Wonju, Republic of Korea.
Junhui ChoResearch & Development Center, Bereum Co., Ltd., Wonju, Republic of Korea.
Jayesh ChaudharyResearch & Development Center, Bereum Co., Ltd., Wonju, Republic of Korea.
Hyun-Dong ShinResearch & Development Center, Bereum Co., Ltd., Wonju, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Overweight is linked to gut microbiota dysbiosis and gastrointestinal (GI) symptoms that impair quality of life. Methods: This 84-day randomized, double-blind, placebo-controlled study evaluated the gut-health effects of heat-killed Results: Compared to placebo, beLP1 Conclusion: Overall, beLP1 Clinical trial registration: https://clinicaltrials.gov/study/NCT05820737?cond=NCT05820, identifier NCT05820737.

Indexed as

digestive symptomsgastrointestinal microbiomeGSRSgut microbiotaLactiplantibacillus plantarumquality of lifestress

Identifiers

PMID42824179
PMCPMC13627065

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.