ArticleNuclear medicine and molecular imaging2026
Enhanced Lymphoma Subtype Classification and Prognosis Using Machine Learning with
Article in Nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This study explored a machine learning approach using Methods: In this cohort study, baseline Results: A total of 156 lymphoma patients were analyzed, with 2,076 lesions segmented and 200 radiomic features extracted. For subtype classification, AdaBoost achieved the highest AUC for Diffuse Large B-cell (DLBCL) (0.863, accuracy 0.742), while XGBoost performed best for High-Grade Non-Hodgkin lymphoma (NHL) (AUC 0.825, accuracy 0.735) and Nodular Sclerosis Hodgkin Lymphoma (NS-HL) (AUC 0.827, accuracy 0.832). Logistic regression showed the best results for Classical Hodgkin Lymphoma (C-HL) (AUC 0.849, accuracy 0.775). The SUV Conclusion: Radiomic features combined with machine learning significantly improve lymphoma subtype classification over SUV Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1007/s13139-026-01017-4.
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