Evidence map›Paper›PMID 42824776›Full record

ReviewFrontiers in immunology2026

Metabolic dysfunction and GZMK

Qianqian Zhong, Wanruo Lyu, Jieying Li, Yiming Song, Yunxin Huang, Chunbin Wang, Juling Ji

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qianqian ZhongDepartment of Pathology, Medical School of Nantong University, Nantong, Jiangsu, China.
Wanruo LyuDepartment of Pathology, Medical School of Nantong University, Nantong, Jiangsu, China.
Jieying LiDepartment of Pathology, Medical School of Nantong University, Nantong, Jiangsu, China.
Yiming SongDepartment of Pathology, Medical School of Nantong University, Nantong, Jiangsu, China.
Yunxin HuangDepartment of Pathology, Medical School of Nantong University, Nantong, Jiangsu, China.
Chunbin WangDepartment of Oncology, The Sixth Affiliated Hospital of Nantong University, Yanchen, Jiangsu, China.
Juling JiDepartment of Pathology, Medical School of Nantong University, Nantong, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus and metabolic dysfunction associated steatotic liver disease contribute to the growing burden of hepatocellular carcinoma, yet their effects on hepatic antitumor immunity remain incompletely defined. Recent single-cell and spatial profiling studies indicate that hepatocellular carcinoma contains diverse CD8

Indexed as

Carcinoma, HepatocellularCD8-Positive T-LymphocytesLiver NeoplasmsAnimalsDiabetes Mellitus, Type 2HumansTumor MicroenvironmentCD8+ T cellsGZMKhepatocellular carcinomaimmunometabolismtumor microenvironment

Identifiers

PMID42824776
PMCPMC13627992

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.