Evidence map›Paper›PMID 42827177›Full record

ArticleInternational urogynecology journal2026

Ecological Momentary Assessment Reveals Greater Anxiety and Marked Instability of Urinary Urgency in Overactive Bladder.

Lindsey C McKernan, Benjamin N Johnson, Aaron X Lee, Tatsuki Koyama, A Grace Kelly, Stephen Bruehl, Roger R Dmochowski, Elisabeth M Sebesta

Abstract read
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In one paragraph

Article in International urogynecology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lindsey C McKernanDepartment of Psychiatry & Behavioral Sciences, Vanderbilt University Medical Center, Osher Center for Integrative Health, 3401 West End Avenue, Suite 380, Nashville, TN, 37203, USA. lindsey.mckernan@vumc.org.
Benjamin N JohnsonMarion Turpan College of Psychology and Counseling, Fairleigh Dickinson University, 1000 River Road, WH 104H, Teaneck, NJ, 07666, USA. b.johnson2@fdu.edu.ORCID http://orcid.org/0000-0002-3050-7043
Aaron X LeeDepartment of Biostatistics, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 1100, Nashville, TN, 37203, USA.
Tatsuki KoyamaDepartment of Biostatistics, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 1100, Nashville, TN, 37203, USA.
A Grace KellyDepartment of Psychiatry & Behavioral Sciences, Vanderbilt University Medical Center, Osher Center for Integrative Health, 3401 West End Avenue, Suite 380, Nashville, TN, 37203, USA.
Stephen BruehlDepartment of Anesthesiology, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN, 37232, USA.
Roger R DmochowskiDepartment of Urology, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN, 37232, USA.
Elisabeth M SebestaDepartment of Urology, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN, 37232, USA.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
NCATS NIH HHS UL1 TR002243NIDDK NIH HHS DK128293NIDDK NIH HHS DK129624
6 · The paper itself

Abstract

introduction and hypothesisOveractive bladder (OAB) is highly prevalent and frequently co-occurs with anxiety. Although cross-sectional studies associate anxiety and OAB symptoms, anxiety and lower urinary tract symptoms (LUTS) vary in daily life. We applied ecological momentary assessment (EMA), consisting of four brief surveys administered via participants' smartphones over 7-14 days, to characterize severity and variability of anxiety and LUTS among individuals with and without OAB, and by sex among those with OAB.

methodsThree hundred thirty-one participants with active OAB symptoms and healthy controls (HC) (271 OAB, 60 HC) (M age = 47.0, 69% White) from two studies of OAB completed baseline measures and 322 completed EMA evaluating affective symptoms (e.g., anxiety) and LUTS (e.g., urgency, frequency). Analyses compared OAB to HC, and sexes within OAB on aggregated momentary affective and LUTS ratings reflecting symptom intensity, variability, and instability.

resultsDespite equivalent cross-sectional anxiety ratings, OAB participants displayed significantly more severe, variable, and unstable anxiety than HC in EMA, with medium effects (p < 0.001, d = .48-.55). Urinary urgency was the most unstable LUTS in OAB, fluctuating roughly 7 points on an 11-point scale. While women reported more incontinence-related symptoms, men reported greater average frequency.

conclusionsOur findings confirm cross-sectional evidence for increased psychological and urinary burden and provide novel evidence of substantial fluctuations in distress and urinary symptoms in OAB patients. Findings suggest exploring mechanistic links between psychological and urinary symptoms and highlight the utility of EMA as an assessment tool in OAB.

Indexed as

Ambulatory assessmentAnxietyEcological momentary assessmentIntensive longitudinal assessmentLower urinary tract symptomsOveractive bladder

Identifiers

PMID42827177

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.