ArticleFrontiers in surgery2026
Rheumatoid arthritis and risks of postoperative adverse events after posterior lumbar interbody fusion for lumbar degenerative diseases: a retrospective cohort study with matched controls.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To explore the correlation between rheumatoid arthritis (RA) and postoperative complications, long-term pain relief and functional recovery in patients undergoing posterior lumbar interbody fusion (PLIF) for lumbar degenerative diseases. Methods: A single-center 1:3 matched retrospective cohort study was conducted. From January 2015 to September 2020, 32 PLIF patients with confirmed RA were included in the exposed group, and 96 non-RA (NRA) PLIF patients were matched by age, gender, body mass index and single/double fusion segment. Binary logistic regression was performed to identify independent risk factors for complications, and unadjusted odds ratios (OR), relative risks (RR) with 95% confidence interval were calculated for each adverse event. All patients completed ≥2-year clinical and imaging follow-up. Results: All patients acquired immediate short-term postoperative pain reduction; however, RA group exhibited progressive recurrent back and leg pain during long-term follow-up. The postoperative and final follow-up visual analog scale for back and leg pain were significantly higher in the RA group than in the NRA group ( Conclusion: RA is correlated with significantly elevated risks of multiple adverse events following PLIF for lumbar degenerative diseases.
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