Evidence map›Paper›PMID 42835142›Full record

ArticleFrontiers in medicine2026

Clinical usefulness of objective tongue image devices monitoring in temporal tongue color: a demonstration of successively treated cases with traditional medicines.

Aya Murakami, Takao Namiki, Atsushi Ishige, Sadayuki Ochi, Monika Suzuki, Akira Morita, Tatsuro Katsuno, Akihide Sumino, Kohsuke Hayamizu, Toshiya Nakaguchi

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Aya MurakamiLaboratory of Food Chemistry, Yokohama University of Pharmacy, Yokohama, Japan.
Takao NamikiCenter for Preventive Medicine, International University of Health and Welfare, Narita Hospital, Chiba, Japan.
Atsushi IshigeYokohama University of Pharmacy, Yokohama, Japan.
Sadayuki OchiDepartment of Health Pharmacy, Yokohama University of Pharmacy, Yokohama, Japan.
Monika SuzukiDepartment of Medical Engineering, Graduate School of Science and Engineering, Chiba University, Chiba, Japan.
Akira MoritaSumida Kampo Clinic, Chiba University Hospital, Tokyo, Japan.
Tatsuro KatsunoSumida Kampo Clinic, Chiba University Hospital, Tokyo, Japan.
Akihide SuminoLaboratory of Food Chemistry, Yokohama University of Pharmacy, Yokohama, Japan.
Kohsuke HayamizuLaboratory of Food Chemistry, Yokohama University of Pharmacy, Yokohama, Japan.
Toshiya NakaguchiCenter for Frontier Medical Engineering, Chiba University, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In Kampo medicine (traditional Japanese medicine), the diagnostic method of observing a patient's tongue is called the 'tongue diagnosis'. Information provided by observation of a patient's tongue is used to help select prescriptions at the initial consultation, monitor treatment effectiveness after therapy begins, and determine whether prescriptions should be changed. Kampo practitioners must therefore accurately compare the patient's past tongue condition with the current condition. However, it can be difficult to remember the precise details regarding a patient's previous tongue's appearance and to consistently make accurate comparisons. Given the need for objective and reproducible method of documenting tongue findings, we investigated the usefulness of our developed Tongue Image Analyzing System (TIAS). The application of the TIAS for two representative patients is described herein. Methods: We retrospectively reviewed patients who underwent tongue photography after providing informed consent and selected two cases with contrasting degrees of longitudinal changes in tongue findings. One patient demonstrated subtle changes in tongue color that were difficult to detect with the naked eye, and the other patient showed marked tongue color changes accompanied by changes in the heterogeneity of the tongue coating. We obtained the tongue color values in each case from tongue images photographed by TIAS as RGB data and converted into the CIE L*a*b* color space. Results: The tongue color of case1 was analyzed at three time points. The color difference from the first consultation (calculated as Conclusion: TIAS enables standardized longitudinal tongue imaging and facilitates the objective and quantitative comparison of subtle changes in tongue color that may be difficult to discern visually. These findings suggest that TIAS may be useful for objectively documenting and comparing longitudinal changes in tongue findings in clinical practice.

Indexed as

Kampo medicinetongue colortongue diagnosistongue image analyzing systemtraditional Japanese medicine

Identifiers

PMID42835142
PMCPMC13634951

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.