Evidence map›Paper›PMID 42835783›Full record

ArticleISME host microbe2026

Transplant of cryopreserved mosquito gut microbiota reveals strain-specific patterns of microbial acquisition and assembly.

Holly L Nichols, Vishaal Dhokiya, Ananya F Hoque, Eva Heinz, Grant L Hughes, Kerri L Coon

Abstract read
In one paragraph

Article in ISME host microbe, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Holly L NicholsDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, United States.
Vishaal DhokiyaDepartments of Vector Biology and Tropical Disease Biology, Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
Ananya F HoqueDepartments of Vector Biology and Tropical Disease Biology, Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
Eva HeinzStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G1 1XQ, United Kingdom.
Grant L HughesDepartments of Vector Biology and Tropical Disease Biology, Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
Kerri L CoonDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, United States.ORCID https://orcid.org/0000-0002-2701-5195

Funding

Exploiting gnotobiotic systems to examine microbiota acquisition in mosquitoes and for microbiome transplantationsR21AI138074 · NIAID · TMLIVERPOOL SCHOOL OF TROPICAL MEDICINE · PI HUGHES, GRANT LESLIE · 2018 to 2019
$296k
NIAID NIH HHS R21 AI138074
6 · The paper itself

Abstract

Mosquitoes are important vectors of human pathogens, and their gut microbiome influences traits such as survival, fecundity, pathogen resistance, insecticide resistance, and vector competence. Manipulating this microbiome offers a promising strategy for reducing mosquito-borne disease. While 16S rRNA gene amplicon sequencing has revealed global patterns of gut microbial diversity, the factors driving these patterns remain poorly understood. Here, we used a community-transplantation approach that allows the collection, cryopreservation, and transfer of whole adult microbial communities into axenic (germ-free) mosquitoes to investigate the determinants of microbiome assembly and host-microbe interactions. Using reciprocal transplants between

Indexed as

Aedes aegyptihost−microbeinsectmicrobiota transplantmosquito microbiome

Identifiers

PMID42835783
PMCPMC13637714

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.