Evidence map›Paper›PMID 42836659›Full record

ArticleAdipocyte2026

Cinnamaldehyde combined with 18β-glycyrrhetinic acid promotes the differentiation of C3H10T1/2 MSCs into thermogenic adipocytes through PGC1α/FNDC5/UCP1 pathway.

Tingting Lai, Yi Lin, Fuping Ding, Zhenni Shi, Jun Zhang, Yongjin Yan, Shunzhong Gu, Kunting Zhong, Jinhong Liu, Weiyu Liang and 4 more

Abstract read
In one paragraph

Article in Adipocyte, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tingting LaiResearch Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Yi LinResearch Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Fuping DingSchool of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, China.
Zhenni ShiSchool of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, China.
Jun ZhangDepartment of Orthopedics, Kunming Traditional Chinese Medicine Hospital, Kunming, Yunnan, China.
Yongjin YanDepartment of Cardiology, Haian People's Hospital, Haian, Jiangsu, China.
Shunzhong GuDepartment of Cardiology, Haian People's Hospital, Haian, Jiangsu, China.
Kunting ZhongResearch Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Jinhong LiuResearch Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Weiyu LiangResearch Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Yilin DuanResearch Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Zhanhui HuangDepartment of Gastroenterology, Shanwei Yihui Foundation Hospital, Shanwei, China.
Shuhe ZhangResearch Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Jin ZhangResearch Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Finding bioactive substances that can promote the

Indexed as

AcroleinAdipocytesCell DifferentiationFibronectinsGlycyrrhetinic AcidMesenchymal Stem CellsPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaThermogenesisUncoupling Protein 1AnimalsCell LineMiceSignal Transduction18alpha-glycyrrhetinic acidAcroleincinnamaldehydeFibronectinsFNDC5 protein, mouseGlycyrrhetinic AcidPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, mouseUcp1 protein, mouseUncoupling Protein 118β-glycyrrhetinic acidC3H10T1/2 MSCsCinnamaldehydeFNDC5thermogenic adipocytes

Identifiers

PMID42836659
PMCPMC13644609

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.