Evidence map›Paper›PMID 42840623›Full record

ReviewFrontiers in endocrinology2026

Living with early-onset type 2 diabetes in young adulthood: a narrative review of lived experience and implications for developmentally appropriate care.

Joel Song Rui Goh, Li Xuan Sim, Ian W Seetho, Shih Ling Kao, Run Ting Chin, Chin Meng Khoo, Amanda Yuan Ling Lim, Pei Chia Eng

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joel Song Rui GohLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Li Xuan SimLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Ian W SeethoDivision of Endocrinology, Department of Medicine, National University Hospital, Singapore, Singapore.
Shih Ling KaoDivision of Endocrinology, Department of Medicine, National University Hospital, Singapore, Singapore.
Run Ting ChinDivision of Endocrinology, Department of Medicine, National University Hospital, Singapore, Singapore.
Chin Meng KhooDivision of Endocrinology, Department of Medicine, National University Hospital, Singapore, Singapore.
Amanda Yuan Ling LimDivision of Endocrinology, Department of Medicine, National University Hospital, Singapore, Singapore.
Pei Chia EngDivision of Endocrinology, Department of Medicine, National University Hospital, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Early-onset Type 2 Diabetes Mellitus (T2DM), defined as diabetes diagnosis before 40 years old, is associated with substantial lifetime cardiometabolic risk. Although many challenges of living with T2DM are shared across adulthood, diagnosis during young adulthood may shape how this condition is perceived, prioritised and managed during a formative stage of life. This narrative review aimed to synthesize how adults diagnosed with T2DM between 18 and 39 years of age experience, understand and manage their condition, and the implications for developmentally appropriate clinical care. Methods: We conducted a structured narrative review of English-language qualitative, mixed-methods and observational quantitative studies identified in PubMed, MEDLINE (via Ovid) and EMBASE (via Ovid) from database inception to 31 August 2025. Direct evidence from adults diagnosed at 18 to 39 years was prioritised. Studies of adults aged ≥18 years with youth-onset T2DM were used as closely related supporting evidence, and broader adult T2DM studies as contextual evidence. Study selection, extraction and appraisal followed predefined procedures, with reporting informed by SANRA. Results: Recurring themes included difficulty integrating diabetes into identity, stigma, competing work and family demands, material hardships, family and sociocultural influences and healthcare services perceived as not aligned with young adults' priorities. Young adults valued practical and age-appropriate communication, flexible appointment scheduling, credible digital education and peer support. However, much of this evidence was cross-sectional or derived from small, single-site qualitative studies and intervention evidence was limited. Conclusion: Although many challenges overlap with the broader T2DM population, they may have particular significance when diabetes develops during young adulthood. Developmentally appropriate care should combine cardiometabolic risk management with flexible, collaborative and non-stigmatizing support. Prospective studies are needed to test whether such models improve patient-reported, clinical and health-service outcomes.

Indexed as

Diabetes Mellitus, Type 2AdolescentAdultAge of OnsetHumansSocial StigmaYoung Adultdevelopmentally appropriate careearly-onset type 2 diabetes mellituslived experienceself-managementstigmayoung adulthood

Identifiers

PMID42840623
PMCPMC13640145

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.