ReviewQuantitative biology (Beijing, China)2026
Technologies for engineering repetitive DNA.
Review in Quantitative biology (Beijing, China), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long-read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth. Nevertheless, engineering repetitive DNA is mainly limited by repeat instability. Despite these challenges, advances have been reported in the construction of short tandem repeats and the large-scale duplication of genes. This review provides a comprehensive overview of current strategies for constructing repetitive DNA, covering both in vitro approaches, including restriction endonuclease ligation, in vitro homologous recombination, and redundancy-minimizing sequences, as well as in vivo methodologies in
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