Evidence map›Paper›PMID 42852169›Full record

ArticleOral oncology reports2026

Programmed cell death ligand 2 (PD-L2) expression is inversely correlated with human papillomavirus status in oropharyngeal squamous cell carcinoma (OPSCC) tumors.

Jeff J Johnson, Wanrui Wang, Zonggao Shi, Annie Roble, Brian Crowley, Madison McFarland, Jing Yang, Daniel L Miller, Mark W Lingen, M Sharon Stack

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oral oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jeff J JohnsonDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, USA.
Wanrui WangDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, USA.ORCID 0009-0008-7898-2717
Zonggao ShiDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Annie RobleHarper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA.
Brian CrowleyHarper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA.
Madison McFarlandHarper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA.
Jing YangDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, USA.
Daniel L MillerDepartment of Pathology and Immunology, Washington University, St. Louis, MO, USA.ORCID 0000-0002-2104-4614
Mark W LingenDepartment of Pathology, University of Chicago, Chicago, IL, USA.
M Sharon StackDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, USA.ORCID 0000-0003-4563-7390

Funding

MicroRNA Profiling and Tumor Progression in HPV+ Oropharyngeal CancerF31DE021926 · NIDCR · UNIVERSITY OF MISSOURI-COLUMBIA · PI MILLER, DANIEL L · 2011 to 2013
$94k
NIDCR NIH HHS F31 DE021926
6 · The paper itself

Abstract

The incidence of oropharyngeal squamous cell carcinoma (OPSCC) associated with infection by the human papillomavirus (HPV) continues to increase and 71% of OPSCC cases in the United States are HPV+. We have previously performed microRNA profiling of HPV+

Indexed as

CheckpointHuman papillomavirusImmunotherapyOropharangeal squamous cell carcinomaProgrammed cell death ligand-2

Identifiers

PMID42852169
PMCPMC13649324

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.