DFT Simulation of the Vibrational Spectrum of Cholesteryl Esters: A New Physical Therapy Proposal for Localized Laser-Based Clearance of Atherosclerotic Lipid Plaques.

Yifan Guan, Yitong Wang, Yawen Li, Yuqi Xia, Zhengfei Wen, Zhe Wang, Kai Li, Peng Zhang

Abstract read

In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yifan GuanShandong Provincial Key Laboratory of Nuclear Science, Nuclear Energy Technology and Comprehensive Utilization, Weihai Frontier Innovation Institute of Nuclear Technology, Shandong University, Weihai 264209, China.

Yitong WangShandong Provincial Key Laboratory of Nuclear Science, Nuclear Energy Technology and Comprehensive Utilization, Weihai Frontier Innovation Institute of Nuclear Technology, Shandong University, Weihai 264209, China.

Yawen LiSchool of Space Science and Technology, Shandong University, Weihai 264209, China.

Yuqi XiaSchool of Space Science and Technology, Shandong University, Weihai 264209, China.

Zhengfei WenSchool of Space Science and Technology, Shandong University, Weihai 264209, China.

Zhe WangSchool of Space Science and Technology, Shandong University, Weihai 264209, China.

Kai LiSchool of Space Science and Technology, Shandong University, Weihai 264209, China.

Peng ZhangShandong Provincial Key Laboratory of Nuclear Science, Nuclear Energy Technology and Comprehensive Utilization, Weihai Frontier Innovation Institute of Nuclear Technology, Shandong University, Weihai 264209, China.ORCID https://orcid.org/0000-0002-1099-6310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholesteryl ester deposition in atherosclerosis (AS) plaques drives lipid core formation and plaque instability. Traditional statin drugs lack targeting and cause adverse reactions in some patients. This study proposed a potential localized laser-based physical intervention strategy based on photon-phonon resonant absorption (PPRA). We assigned the vibrational modes of four cholesteryl esters: cholesteryl linoleate (CLA), cholesteryl oleate (COA), cholesteryl palmitate (CPA), and cholesteryl stearate (CSA) using first-principles density functional theory, and determined the CO vibration frequencies (1720-1750 cm

Identifiers

PMID42852214

DOI10.1021/acsomega.6c02763

PMCPMC13647326

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.