ArticleACS omega2026
Quercetin-Driven Redox Sensitization Enhances the Antitumor Activity of a Thiol-Reactive Agent through Glutathione Disruption.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
Funding
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Abstract
Targeting redox homeostasis represents a promising strategy to overcome adaptive mechanisms that sustain cancer cell survival under therapeutic stress. Here, we evaluated a pharmacological sensitization strategy based on quercetin (Q) preconditioning followed by treatment with 3',5'-dimaleamylbenzoic acid (DMAB), aimed at exploiting glutathione-dependent vulnerabilities in cervical cancer cells. Q and DMAB exhibited synergistic interactions across a 6 × 6 concentration matrix, with a marked leftward shift in the dose-response profile within the IC
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Registered trials
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