Evidence map›Paper›PMID 42853390›Full record

ArticleAnalytical and bioanalytical chemistry2026

Development of a high-specificity nanobody-based enzyme-linked immunosorbent assay for the rapid detection of mebendazole residues.

Yin Li, Baoyi Wang, Zexuan Wang, Wenjing Yan, Fang Tang, Jinxin He

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yin LiShanxi Key Laboratory of Animal Disease Research, Prevention and Control, College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Jinzhong, Shanxi, 030801, PR China.
Baoyi WangShanxi Key Laboratory of Animal Disease Research, Prevention and Control, College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Jinzhong, Shanxi, 030801, PR China.
Zexuan WangShanxi Key Laboratory of Animal Disease Research, Prevention and Control, College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Jinzhong, Shanxi, 030801, PR China.
Wenjing YanShanxi Key Laboratory of Animal Disease Research, Prevention and Control, College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Jinzhong, Shanxi, 030801, PR China.
Fang TangShanxi Key Laboratory of Animal Disease Research, Prevention and Control, College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Jinzhong, Shanxi, 030801, PR China.
Jinxin HeShanxi Key Laboratory of Animal Disease Research, Prevention and Control, College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Jinzhong, Shanxi, 030801, PR China. hjx@sxau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mebendazole (MBZ) residues in animal-derived foods pose significant public health risks, necessitating robust monitoring tools. In this study, a high-specificity nanobody (Nb) against MBZ was isolated from an alpaca-derived phage display library. The selected Nb exhibited superior thermal stability, retaining over 90% of its binding activity even after 40 min of incubation, and maintaining more than 60% activity after 90 min, whereas conventional rabbit IgG and chicken IgY against MBZ lost all activity under identical conditions. A competitive ELISA developed using this Nb achieved an IC

Indexed as

Competitive ELISAFood safetyMebendazoleNanobodyResidue detection

Identifiers

PMID42853390

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.