Observational studyFrontiers in neurology2026
A longitudinal study on the impact of stroke patients' perception trajectories of disease recurrence on short-term clinical outcomes.
Observational study in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Objective: To investigate heterogeneous trajectories of recurrence risk perception among stroke patients within 6 months after discharge and their correlation with short-term clinical outcomes. Methods: A prospective observational study was conducted from February 2023 to October 2025 at the Sixth People's Hospital of Nantong. Of 487 consecutive acute stroke patients screened, 262 met eligibility and provided informed consent, and 240 completed all four follow-ups and were included. Risk perception was assessed using the Stroke Recurrence Risk Assessment Scale at discharge and at 1, 3, and 6 months post-discharge. Clinical outcomes were evaluated using the modified Rankin Scale (mRS), NIHSS, Barthel Index (BI), and Stroke-Specific Quality of Life Scale (SS-QOL). Latent class growth analysis identified risk perception trajectories, and multivariable regression examined associations between trajectories and outcomes. Results: Four distinct risk perception trajectories were identified: the sustained low-risk perception group (35.0%, Conclusion: Heterogeneous developmental trajectories of recurrence risk perception exist among stroke patients, and the "delayed high-risk perception" trajectory is significantly associated with adverse short-term clinical outcomes. Dynamic monitoring of changes in patients' risk perception in clinical practice may help identify high-risk individuals and thus provide a reference for early psychological intervention.
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