Evidence map›Paper›PMID 42857766›Full record

ArticleInternational journal of surgery case reports2026

Superficial squamous cell carcinoma arising in Laimer's diverticulum: a rare case highlighting the importance of anatomical differentiation.

Kenichi Ishizu, Masaaki Saito, Yasuaki KImura, Iku Abe, Hisashi Oshiro, Toshiki Rikiyama

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In one paragraph

Article in International journal of surgery case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kenichi IshizuDepartment of Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Masaaki SaitoDepartment of Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Yasuaki KImuraDepartment of Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Iku AbeDepartment of Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Hisashi OshiroDepartment of Pathology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Toshiki RikiyamaDepartment of Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Laimer's diverticulum (LD) is a rare pharyngoesophageal diverticulum that originates from the posterior wall of the cervical esophagus and beneath the cricopharyngeal muscle (CPM). Carcinoma arising in pharyngoesophageal diverticula occurs predominantly in association with Zenker's diverticulum (ZD), whereas its occurrence in LD is exceptionally rare. We report a rare case of superficial squamous cell carcinoma that originated in LD. Case presentation: A 78-year-old man with a known esophageal diverticulum presented with a 9-year history of progressive dysphagia and regurgitation of food. Esophagography and contrast-enhanced computed tomography demonstrated a large posterior diverticulum originating from the cervical esophagus below the cricoid cartilage. Diverticulectomy was performed through a left cervical approach. Intraoperative findings confirmed that the diverticulum originated from the posterior wall of the cervical esophagus, inferior to the CPM, consistent with LD. Histopathological examination revealed an intra-diverticular 15 mm × 10 mm squamous cell carcinoma Discussion: Accurate anatomical differentiation among types of cervical esophageal diverticula is essential because treatment strategies may differ substantially among LD, ZD, and Killian-Jamieson diverticulum. Endoscopic identification may be difficult because retained food debris, chronic inflammatory changes, and the narrow diverticular lumen can conceal superficial lesions; meticulous cleaning and enhanced endoscopic observation, including narrow-band imaging or Lugol chromoendoscopy, may improve detection in similar cases. Misdiagnosis of LD as ZD may result in inappropriate treatment selection, particularly when endoscopic septotomy is considered. Conclusion: We report a rare case of superficial squamous cell carcinoma originating in LD. Careful anatomical assessment is essential for accurate diagnosis and appropriate surgical management of cervical esophageal diverticula. This case underscores the importance of early surgical excision or regular surveillance when cervical esophageal diverticula are managed nonoperatively.

Indexed as

cervical esophageal diverticulumdiverticulectomyLaimer’s diverticulumsquamous cell carcinomaZenker’s diverticulum

Identifiers

PMID42857766
PMCPMC13652380

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.