A Janus bacterial cellulose patch with antibacterial, antioxidant, anti-inflammatory and angiogenic activities for enhanced oral ulcer healing.

Guning Wang, Jingyu Yan, Chenying Cui, Lihong Zhou, Xiuping Wu, Bing Li

Abstract read

In one paragraph

Article in Regenerative biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guning WangShanxi Medical University School and Hospital of Stomatology and Shanxi Provincial Engineering Research Center for Oral Biomaterials, Taiyuan 030001, Shanxi, China.

Jingyu YanShanxi Medical University School and Hospital of Stomatology and Shanxi Provincial Engineering Research Center for Oral Biomaterials, Taiyuan 030001, Shanxi, China.

Chenying CuiShanxi Medical University School and Hospital of Stomatology and Shanxi Provincial Engineering Research Center for Oral Biomaterials, Taiyuan 030001, Shanxi, China.

Lihong ZhouShanxi Medical University School and Hospital of Stomatology and Shanxi Provincial Engineering Research Center for Oral Biomaterials, Taiyuan 030001, Shanxi, China.

Xiuping WuShanxi Medical University School and Hospital of Stomatology and Shanxi Provincial Engineering Research Center for Oral Biomaterials, Taiyuan 030001, Shanxi, China.

Bing LiShanxi Medical University School and Hospital of Stomatology and Shanxi Provincial Engineering Research Center for Oral Biomaterials, Taiyuan 030001, Shanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral ulcers are complex mucosal lesions characterized by infection, inflammatory imbalance, elevated oxidative stress and impaired vascular regeneration, with therapeutic efficacy hindered by rapid drug loss in the highly wet and dynamic oral environment. Here, we developed a Janus-structured bacterial cellulose (BC)-based multifunctional oral patch (Ber@ZIF/BC, BZB) for stable retention and controlled release of Ber@ZIF (BZ) at ulcer sites. Encapsulation of berberine within ZIF and incorporation into Janus BC endowed the system with robust wet adhesion and microenvironment-responsive drug release.

Indexed as

antibacterialanti-inflammatoryJanus bacterial cellulosemultifunctional patchoral ulcer

Identifiers

PMID42859697

DOI10.1093/rb/rbag160

PMCPMC13653682

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.