Evidence map›Paper›PMID 42859816›Full record

ReviewDrug design, development and therapy2026

Potential Relevance of

Iyan Sopyan, Endang Lukitaningsih, Rachmat Mauludin, Sani Ega Priani, Virginia Heaven Mariboto Siagian, Johnessa Cung, Muhammad Syahrul, Miranda Cania Sirait

Abstract readReview
In one paragraph

Review in Drug design, development and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Iyan Sopyan *Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia.ORCID 0000-0001-7616-5176
Endang Lukitaningsih *Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Gadjah Mada, Sekip Utara, Yogyakarta, 55281, Indonesia.
Rachmat Mauludin *School of Pharmacy, Bandung Institute of Technology, Bandung, 40132, Indonesia.
Sani Ega Priani *Pharmacy Department, Bandung Islamic University (UNISBA), Bandung, Indonesia.ORCID 0000-0001-6544-5463
Virginia Heaven Mariboto Siagian *Apothecary Profession Program, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia.ORCID 0009-0009-6230-2446
Johnessa Cung *Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia.ORCID 0009-0003-2154-1842
Muhammad Syahrul *Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia.
Miranda Cania Sirait *Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by epidermal barrier dysfunction, immune dysregulation, oxidative stress, microbial dysbiosis, and persistent inflammation. Although current therapies have improved disease management, long-term treatment remains challenging because of disease relapse, adverse effects, treatment costs, and variability in therapeutic response. These challenges have stimulated interest in botanical agents with diverse phytochemical profiles and potentially complementary biological activities.

Indexed as

Anti-Inflammatory AgentsBidensDermatitis, AtopicDrug DevelopmentPhytochemicalsPlant ExtractsAnimalsHumansAnti-Inflammatory AgentsPhytochemicalsPlant Extractsatopic dermatitisBidens pilosabotanical medicinepharmacological activitiesphytochemicals

Identifiers

PMID42859816
PMCPMC13653635

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.