Evidence map›Paper›PMID 42860424›Full record

ArticleNature communications2026

A topographic protomap in mouse subplate neurons precedes the onset of sensory experience.

Travis A Babola, Minzi Chang, Rachel Jun, Marina Cardoso de Oliveira, Jessica E Messier, Yunru Chen, Lillian Choi, Dave R Gutierrez, Patrick O Kanold

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Travis A Babola *Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0003-4440-5029
Minzi Chang *Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0001-6121-1782
Rachel JunDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.
Marina Cardoso de OliveiraDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0003-4143-3745
Jessica E MessierDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Yunru ChenDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.
Lillian ChoiDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.
Dave R GutierrezDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.ORCID 0009-0009-5291-7789
Patrick O KanoldDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. pkanold@jhu.edu.ORCID 0000-0002-7529-5435

Funding

NEURONAL CIRCUITS AND PLASTICITY OF NEONATAL AUDITORY CORTEXR01DC009607 · NIDCD · UNIV OF MARYLAND, COLLEGE PARK · PI PATRICK O KANOLD · 2009 to 2026
$7.8M
Plasticity of Functional Networks in Auditory CortexF32DC019842 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI BABOLA, TRAVIS AUSTIN · 2021 to 2022
$136k
NIDCD NIH HHS F32 DC019842NIDCD NIH HHS R01 DC009607U.S. Department of Health & Human Services | NIH | National Institute on Deafness and Other Communication Disorders (NIDCD) F32DC019842U.S. Department of Health & Human Services | NIH | National Institute on Deafness and Other Communication Disorders (NIDCD) R01DC009607
6 · The paper itself

Abstract

Within sensory systems, thalamic projections to layer 4 (L4) neurons establish precise neocortical topography. During development, thalamic axons first synapse onto subplate neurons (SPNs) beneath the cortical plate, however, how thalamic inputs are organized within the subplate is unknown. To examine SPN organization and activity, we generated an inducible Cplx3-CreER mouse driver line to examine SPNs during development. Before sensory onset, we found that Cplx3

Indexed as

Auditory CortexNeuronsThalamusVisual CortexAcoustic StimulationAnimalsFemaleMiceMice, Transgenic

Identifiers

PMID42860424
PMCPMC13655162

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.