Evidence map›Paper›PMID 42864419›Full record

ReviewRadiologie (Heidelberg, Germany)2026

[Varicocele: comparison of minimally invasive treatment options : Endovascular embolization, microsurgery, and patient-tailored treatment selection].

Michael Christian Doppler, Michael Brönnimann, Matthias Jung, Wibke Uller, Elif Can

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Radiologie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael Christian DopplerSektion Interventionelle Radiologie, Klinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Hugstetter Straße 55, 79106, Freiburg, Deutschland.
Michael BrönnimannUniversitätsinstitut für Diagnostische, Interventionelle und Pädiatrische Radiologie (DIPR), Inselspital, Universitätsspital Bern, Universität Bern, Bern, Schweiz.
Matthias JungSektion Interventionelle Radiologie, Klinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Hugstetter Straße 55, 79106, Freiburg, Deutschland.
Wibke UllerSektion Interventionelle Radiologie, Klinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Hugstetter Straße 55, 79106, Freiburg, Deutschland.
Elif CanSektion Interventionelle Radiologie, Klinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Hugstetter Straße 55, 79106, Freiburg, Deutschland. elif.can@uniklinik-freiburg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVaricocele is the most common potentially treatable cause of male subfertility. Endovascular embolization is an established minimally invasive alternative to microsurgical ligation.

objectiveTo place the indications, technique, outcomes, and limitations of varicocele embolization in context and to define its role relative to microsurgery. MATERIALS AND

methodsNarrative, guideline- and evidence-based review of current WHO, EAU, AUA/ASRM, and CIRSE recommendations, systematic reviews, meta-analyses, and relevant cohort studies published through July 2026.

resultsTreatment is primarily indicated in men with a palpable varicocele, abnormal semen parameters, and otherwise unexplained infertility; subclinical varicoceles and normal semen analyses do not justify intervention. Technical success of embolization is usually above 90% in experienced centers. Pregnancy rates are broadly similar to those after surgery, while overall morbidity tends to be lower. Recurrence may, however, be more frequent than after high ligation. No embolic agent has proved consistently superior.

conclusionVaricocele embolization is an evidence-based alternative to surgery, particularly for recurrent disease, bilateral or complex venous anatomy, and when rapid recovery is a priority. Treatment should be selected through multidisciplinary, anatomy-based, and shared decision-making.

Indexed as

Gonadal vein refluxMale infertilitySclerotherapyVaricoceleVenography

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.