Evidence map›Paper›PMID 42865860›Full record

ArticleMedComm2026

O-GlcNAcylation Stimulation Modulates Na+/K+ ATPase and Improves Outcomes in Hemorrhagic Shock.

Thomas Dupas, Amandine Vergnaud, Virginie Aillerie, Martin Bouaud, Angélique Erraud, Thomas Pelé, Antoine Persello, Barbara Ribeiro de Oliveira, Jérôme Montnach, Aurore Girardeau and 14 more

Abstract read
In one paragraph

Article in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Thomas DupasNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.ORCID https://orcid.org/0000-0002-8827-3526
Amandine VergnaudNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Virginie AillerieNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Martin BouaudNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Angélique ErraudNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Thomas PeléNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Antoine PerselloNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Barbara Ribeiro de OliveiraNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Jérôme MontnachNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Aurore GirardeauNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Jules LecomteNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Nolwenn TessierNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Mathilde GuyonNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Angélique Blangy-LetheuleNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Matthieu RivièreNantes Université, CNRS, CEISAM, UMR 6230, 2 Rue De La Houssinière Nantes France.
Jacques LebretonNantes Université, CNRS, CEISAM, UMR 6230, 2 Rue De La Houssinière Nantes France.
Arnaud TessierNantes Université, CNRS, CEISAM, UMR 6230, 2 Rue De La Houssinière Nantes France.
Edith Bigot-CorbelNantes Université, CHU de Nantes, Department of Biochemistry Nantes France.
Aurélia A LerouxNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Michel De WaardNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Nicolas J PratInstitut De Recherche Biomédicale Des Armées (IRBA) Bretigny-sur-Orge France.
Bertrand RozecNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Manon DenisNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.
Benjamin LauzierNantes Université, CHU Nantes, CNRS, INSERM, L'institut Du Thorax Nantes France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemorrhagic shock (HS), caused by blood loss leading to inadequate organ perfusion, remains a major cause of death worldwide, with 1.9 million fatalities annually. It triggers severe disturbances in cardiovascular, neurohormonal, and metabolic homeostasis with ionic imbalance notably due to Na

Indexed as

hemorrhagic shockNa+/K+ ATPaseO‐GlcNAcylationtherapeutic strategy

Identifiers

PMID42865860
PMCPMC13655371

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.