Evidence map›Paper›PMID 42866288›Full record

ReviewFrontiers in neuroscience2026

Mapping dynamics in neuronal activation and molecular connectivity with functional PET.

Andreas Hahn, Murray B Reed, Pia Falb, Matej Murgaš, Christian Milz, Sarah M Tüchler, Sebastian Klug, Godber M Godbersen, Rupert Lanzenberger

Abstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andreas HahnDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Murray B ReedDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Pia FalbDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Matej MurgašDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Christian MilzDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Sarah M TüchlerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Sebastian KlugDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Godber M GodbersenDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Rupert LanzenbergerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The assessment of brain function using PET imaging has recently gained increasing interest due to several technical advancements, including bolus+infusion radiotracer administration protocols combined with hybrid PET/MR or high-sensitive PET/CT scanners. Functional PET (fPET) enables imaging of stimulation-induced changes in glucose metabolism and neurotransmitter action in a single scan as well as computation of molecular connectivity represented by temporal associations of PET signals between brain regions. In addition to methodological considerations, this work aims to highlight key advantages, limitations and future challenges of fPET and applications in multimodal imaging. Regional increases in glucose metabolism largely correspond to those observed with BOLD fMRI across a range of cognitive tasks, whereas divergence within the default mode network during internally directed attention seems to reflect active inhibitory processes. Extensions to radioligands beyond [

Indexed as

dopamine synthesisglucose metabolismmolecular connectivitymultimodal brain imagingserotonin synthesis

Identifiers

PMID42866288
PMCPMC13656004

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.