ArticleClinics in orthopedic surgery2026
Comparative Effects of Acellular Dermal Matrix and Atelocollagen Injections in Intratendinous Partial-Thickness Rotator Cuff Tears: A Retrospective Cohort Study.
Article in Clinics in orthopedic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The purpose was to compare the functional and structural outcomes between injectable acellular dermal matrix (ADM) and atelocollagen in patients with intratendinous partial-thickness rotator cuff tears. Methods: From January 2020 to May 2021, 115 consecutive patients with magnetic resonance imaging (MRI)-confirmed intratendinous partial-thickness supraspinatus tears who met the inclusion criteria were retrospectively identified. After applying predefined exclusion criteria, 85 patients remained for final analysis and were categorized into 2 groups: intratendinous injection with 1 mL ADM (group A, n = 40) and 1 mL type I atelocollagen (group B, n = 45). The visual analog scale (VAS) score for pain, American Shoulder and Elbow Surgeons (ASES) score, Constant Shoulder score (CSS), and range of motion (ROM) were evaluated before injection and at 1, 3, 6, and 9 months and the last follow-up after injection. MRI was performed at 6 months after injection to evaluate rotator cuff integrity and healing response. Results: The mean follow-up period was 14.1 months. Both groups demonstrated significant improvements in pain, functional outcomes, and ROM from baseline to final follow-up. ASES scores increased from 60.3 to 88.4 in group A and from 67.4 to 90.2 in group B (both Conclusions: Both ADM and atelocollagen injections were associated with clinically meaningful improvement in patients with intratendinous partial-thickness rotator cuff tears, with generally maintained MRI-based structural outcomes at follow-up.
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