ReviewCureus2026
Beyond Fertility: Ethical and Psychosocial Dimensions of Fertility Preservation in Children and Adolescents.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This narrative review examines fertility preservation in children and adolescents receiving gonadotoxic treatment for cancer and serious non-malignant conditions, including chemotherapy, radiotherapy, and hematopoietic stem cell transplantation. It considers the impact of these therapies on future reproductive potential and summarizes current fertility preservation strategies according to sex and pubertal status. Established options for postpubertal adolescents are discussed alongside gonadal tissue cryopreservation approaches for prepubertal children and emerging experimental strategies, including insights from animal studies and the uncertainties surrounding the future clinical use of preserved tissue. Particular attention is given to the ethical complexities of fertility preservation in childhood, including informed consent, assent, parental decision-making, evolving autonomy, and procedures with uncertain future benefit. The psychological impact on children, adolescents, and their families is also considered, together with the role of multidisciplinary teams in providing timely, equitable, developmentally appropriate counseling and ongoing psychosocial support. The review concludes that fertility preservation should be regarded not as a single decision made before gonadotoxic treatment, but as a longitudinal process extending from diagnosis through survivorship and into adulthood.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.