Evidence map›Paper›PMID 42888393›Full record

ArticleBMC oral health2026

Comparative evaluation of AI-driven large language models for periodontal-orthodontic patient questions: accuracy, comprehensiveness, readability, and temporal consistency.

Resül Çolak, Merve Küçükoğlu Çolak, Orhan Cicek

Abstract readComparative Study
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Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Resül ÇolakDepartment of Periodontology, Faculty of Dentistry, Zonguldak Bülent Ecevit University, Zonguldak, 67600, Türkiye. r.colak@beun.edu.tr.ORCID http://orcid.org/0000-0001-5210-1119
Merve Küçükoğlu ÇolakDepartment of Periodontology, Faculty of Dentistry, Zonguldak Bülent Ecevit University, Zonguldak, 67600, Türkiye.ORCID http://orcid.org/0000-0002-7652-0016
Orhan CicekDepartment of Orthodontics, Faculty of Dentistry, Zonguldak Bülent Ecevit University, Zonguldak, 67600, Türkiye.ORCID http://orcid.org/0000-0002-8172-6043

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI)-driven large language models (LLMs) are increasingly used to provide patient-oriented oral health information; however, their performance in answering periodontal-orthodontic patient questions remains unclear. This study aimed to compare the performance of contemporary AI-driven LLMs in answering periodontal-orthodontic patient questions by assessing response accuracy, comprehensiveness, readability, and temporal consistency.

methodsThirty patient-oriented periodontal-orthodontic questions were submitted to six contemporary LLMs (ChatGPT 5.5, Claude Sonnet 4.6, DeepSeek 3.2, Gemini 3.1 Pro, Grok 4.20, and PerioGPT) under standardized conditions, and the generated responses were analyzed. Accuracy and comprehensiveness were evaluated using a modified five-point Likert scale, whereas readability was assessed using the Flesch Reading Ease (FRE) and Flesch-Kincaid Grade Level (FKGL) indices. Temporal consistency was assessed by repeating the response-generation process one week later. Inter-model comparisons and temporal consistency analyses were performed using repeated-measures ANOVA or Friedman tests with Bonferroni-adjusted post hoc comparisons, as appropriate.

resultsSignificant differences were observed among the evaluated LLMs in accuracy (p < 0.001, Kendall's W = 0.401), comprehensiveness (p < 0.001, Kendall's W = 0.575), FRE (p < 0.001, partial η

conclusionsWhile PerioGPT and Gemini achieved the highest accuracy and comprehensiveness scores, and Claude, DeepSeek, and Grok produced more readable responses, the evaluated models generally demonstrated similar temporal consistency over time; however, no model consistently outperformed the others across all evaluated criteria. Therefore, AI-driven LLMs may support patient education and oral health literacy in periodontal-orthodontic care; however, their use as complementary tools under expert supervision is recommended.

Indexed as

Artificial IntelligenceLarge Language ModelsOrthodonticsPeriodontal DiseasesComprehensionHumansAccuracyArtificial intelligenceComprehensivenessHealth literacyLarge language modelPatient educationReadabilityTemporal consistency

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.