Evidence mapPaperPMID 4337382Full record

ArticleClinical chemistry1972

Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.

W T Friedewald, R I Levy, D S Fredrickson

15 registry-linked trialsAbstract readComparative Study
PubMed
In one paragraph

Article in Clinical chemistry, 1972. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 15 registered trials, which are not on this map. Cited by 8,760 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8,760citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06827002 phase1 / phase2active not recruitingstarted 2023, after this paper: background citation

Cissus Quadrangularis (CQR-300®) and Dichrostachys Glomerata (Dyglomera®) Extracts Increase GLP-1 Levels and Inhibit Dipeptidyl Phosphate-4 Activity in Healthy Overweight and Obese Adults

Ran2023Enrolled248Registered outcomes8Posted comparisons0ConditionsAppetite Regulation, Obesity and OverweightArmsCissus quadrangularia, Dextrin, Dichrostachys glomerata, Semaglutide (Rybelsus®)
Open the trial in the graph
NCT00595504 phase4completednot on this mapstarted 2008, after this paper: background citation

Phase IV Study of Ramelteon as an Adjunct Therapy in Non-Diabetic Patients With Schizophrenia

TypeinterventionalSponsorMassachusetts General HospitalRan2008 to 2010Enrolled25ConditionsSchizophrenia, Schizoaffective Disorder, Schizophreniform DisordersArmsRamelteon, Placebo
NCT01082588 phase4completednot on this mapstarted 2010, after this paper: background citation

Phase 4 Study of the Effects of Pravastatin on Cholesterol Levels, Inflammation and Cognition in Schizophrenia

TypeinterventionalSponsorMassachusetts General HospitalRan2010 to 2012Enrolled60ConditionsSchizophrenia, Schizoaffective Disorders, Schizophreniform DisordersArmsPravastatin, Placebo
NCT02245399 nacompletednot on this mapstarted 2014, after this paper: background citation

Canola Enriched Mediterranean Type Weight Loss Diet in Type 2 Diabetes

TypeinterventionalSponsorUnity Health TorontoRan2014 to 2017Enrolled164ConditionsType 2 Diabetes, Obesity, Overweight, Cardiovascular DiseasesArmsA canola oil enriched mediterranean diet, A high wheat fiber diet
NCT02529046 nacompletednot on this mapstarted 2007, after this paper: background citation

Effect of Conjugated Linoleic Acid Associated With Aerobic Exercise on Body Fat and Lipid Profile in Obese Women: A Randomized, Double-blinded and Placebo-controlled Trial

TypeinterventionalSponsorUniversidade Estadual de LondrinaRan2007 to 2007Enrolled28ConditionsLipid Metabolism Disorders, ObesityArmsCLA, Placebo
NCT02675101 nacompletednot on this mapstarted 2016, after this paper: background citation

Nuts and Olestra for Persistent Organic Pollutant Reduction (NO-POPs) Trial: A Pilot Investigation

TypeinterventionalSponsorUniversity of California, San DiegoRan2016 to 2019Enrolled45ConditionsPersistent Organic Pollutants, Endocrine Disrupting Chemicals, Endocrine Disruptor EffectsArmsWhole Nuts, Olestra: Fat Free Pringles, Vegetable Oil: Original Pringles
NCT02837666 nacompletednot on this mapstarted 2017, after this paper: background citation

Independent and Synergistic Effect of Spirulina Maxima With Exercise on General Fitness, Lipid Profile and Antioxidant Capacity in Overweight and Obese Subjects

TypeinterventionalSponsorUniversidad Autonoma de Ciudad JuarezRan2017 to 2017Enrolled52ConditionsCardiovascular DiseasesArmsSupplementation with Spirulina maxima, Washout, Supplementation with placebo, Isoenergetic diet, Exercise program
NCT02922062 nacompletednot on this mapstarted 2016, after this paper: background citation

The Effects of Palm Oil Consumed Under Different Macronutrient Distributions on Circulating Lipoprotein and Fatty Acid Profiles

TypeinterventionalSponsorOhio State UniversityRan2016 to 2018Enrolled24ConditionsCardiovascular Diseases, InflammationArmsCanola Oil, Palm Oil, Butter
NCT02923453 phase2completednot on this mapstarted 1998, after this paper: background citation

Efficacy and Safety of American Ginseng (Penax Quinquefolius) Extract on Glycemic Control in Individuals With Type 2 Diabetes: A Double-blind, Randomized, Crossover Clinical Trial

TypeinterventionalSponsorUnity Health TorontoRan1998 to 2002Enrolled23ConditionsType II Diabetes ControlArmsCNT 2000 American ginseng extract, Placebo
NCT03209596 nacompletednot on this mapstarted 2013, after this paper: background citation

Nutritional and Biochemical Effects of Orange Juice Supplementation in Soccer Players: a Double Blind, Randomized and Controlled Trial

TypeinterventionalSponsorEllen Cristini de FreitasRan2013 to 2014Enrolled30ConditionsHealthy AthletesArmsOrange juice (1L/d), Control drink (1L/d)
NCT03424395 nacompletednot on this mapstarted 2017, after this paper: background citation

A Clinical Trial to Evaluate the Effects of Proprietary Personalized Dietary Programs on Markers of Health and Wellness, Body Composition, and Quality of Life

TypeinterventionalSponsorHabit, LLCRan2017 to 2018Enrolled110ConditionsHealthy, MetabolismArmsPersonalized dietary and wellness program
NCT04117750 nacompletednot on this mapstarted 2017, after this paper: background citation

Impact of Vitamin D Supplementation on the Cardiometabolic Status and Androgen Profile in Women With Polycystic Ovary Syndrome: Placebo-Controlled Clinical Trial

TypeinterventionalSponsorZagazig UniversityRan2017 to 2018Enrolled145ConditionsEvaluations, Diagnostic Self, Treatment AdherenceArmscholecalciferol (vit D3)
NCT04222894 nacompletednot on this mapstarted 2020, after this paper: background citation

Hospital Workplace Nutrition Study (Sibley Memorial Hospital)

TypeinterventionalSponsorPhysicians Committee for Responsible MedicineRan2020 to 2021Enrolled22ConditionsOverweight, Type2 DiabetesArmsPlant-based diet, Control Diet
NCT05128747 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Effectiveness of Nutritional Program Intervention for Control of Lipid Profile Among Diabetic Patients

TypeinterventionalSponsorAssiut UniversityRan2022 to 2022Enrolled190ConditionsDyslipidemia Associated With Type II Diabetes MellitusArmsDASH diet
NCT05795439 narecruitingnot on this mapstarted 2023, after this paper: background citation

The CARING Study: Creating and Restoring Health Through Nutrition Guidance

TypeinterventionalSponsorPhysicians Committee for Responsible MedicineRan2023 to 2028Enrolled700ConditionsType2diabetes, Type 2 Diabetes Treated With InsulinArmsLow-fat, vegan diet
3 · Its place in the literature

Who cites it

8,760 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. The perspective of artificial intelligence for NMR.Magnetic resonance letters · 2027
    Review
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8,700 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

W T Friedewald
R I Levy
D S Fredrickson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood Protein DisordersCholesterolFastingHumansHyperlipidemiasLipoproteinsLipoproteins, HDLLipoproteins, LDLLipoproteins, VLDLMathematicsMethodsTriglyceridesUltracentrifugationCholesterolLipoproteinsLipoproteins, HDLLipoproteins, LDLLipoproteins, VLDLTriglycerides

Identifiers

PMID4337382

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

and 9 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.