ArticleProceedings of the National Academy of Sciences of the United States of America1994
Cloning and expression of a cytoskeleton-associated diacylglycerol kinase that is dominantly expressed in cerebellum.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Who cites it
25 citing papers in PubMed, 100 citations in OpenAlex.
- Diacylglycerol Kinases and Its Role in Lipid Metabolism and Related Diseases.International journal of molecular sciences · 2024Review
- Discrete localization of phospholipase Cβ3 and diacylglycerol kinase ι along the renal proximal tubules of normal rat kidney and gentamicin-induced changes in their expression.Histochemistry and cell biology · 2023Article
- Beyond Lipid Signaling: Pleiotropic Effects of Diacylglycerol Kinases in Cellular Signaling.International journal of molecular sciences · 2020Review
- Expression and localization of diacylglycerol kinase ζ in guinea pig cochlea and its functional implication under noise-exposure stress conditions.Histochemistry and cell biology · 2019Article
- Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases: An Update.Frontiers in cell and developmental biology · 2016Review
- Arachidonoyl-Specific Diacylglycerol Kinase ε and the Endoplasmic Reticulum.Frontiers in cell and developmental biology · 2016Review
- Selective localization of diacylglycerol kinase (DGK)ζ in the terminal tubule cells in the submandibular glands of early postnatal mice.Histochemistry and cell biology · 2015Article
- Expression and localization of type II diacylglycerol kinase isozymes δ and η in the developing mouse brain.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2015Article
- Diacylglycerol kinase as a possible therapeutic target for neuronal diseases.Journal of biomedical science · 2014Review
- The expression of diacylglycerol kinase theta during the organogenesis of mouse embryos.BMC developmental biology · 2013Article
- Induction of filopodia-like protrusions in N1E-115 neuroblastoma cells by diacylglycerol kinase γ independent of its enzymatic activity: potential novel function of the C-terminal region containing the catalytic domain of diacylglycerol kinase γ.Molecular and cellular biochemistry · 2013Article
- Involvement of diacylglycerol kinase γ in modulation of iNOS synthesis in Golgi apparatus of vascular endothelial cells.Naunyn-Schmiedeberg's archives of pharmacology · 2012Article
- NMDA receptor-mediated Ca(2+) influx triggers nucleocytoplasmic translocation of diacylglycerol kinase ζ under oxygen-glucose deprivation conditions, an in vitro model of ischemia, in rat hippocampal slices.Histochemistry and cell biology · 2012Article
- Signaling cascade of diacylglycerol kinase β in the pituitary intermediate lobe: dopamine D2 receptor/phospholipase Cβ4/diacylglycerol kinase β/protein kinase Cα.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2010Article
- Signaling at the membrane interface by the DGK/SK enzyme family.Journal of lipid research · 2009Review
- Diacylglycerol kinases in immune cell function and self-tolerance.Immunological reviews · 2008Review
- Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17.Molecular and cellular biology · 2007Article
- Regulation of neurite outgrowth in N1E-115 cells through PDZ-mediated recruitment of diacylglycerol kinase zeta.Molecular and cellular biology · 2005Article
- Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complex.Molecular and cellular biology · 1998Article
- Purification and characterization of sn-1-stearoyl-2-arachidonoylglycerol kinase from pig testes.The Biochemical journal · 1997Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A third species of diacylglycerol kinase (EC 2.7.1.107) cDNA was cloned from a rat brain cDNA library. The isolated cDNA encoded a 788-amino acid, 88-kDa polypeptide. This isozyme shared 58% identity with the previously isolated rat 80-kDa and 90-kDa diacylglycerol kinases. EF hand motifs, cysteine-rich zinc finger-like sequences, and putative ATP-binding site were all conserved among these isozymes. The 88-kDa diacylglycerol kinase was expressed specifically in brain and localized predominantly in cerebellar Purkinje cells. This isozyme was associated equally with particulate and supernatant fractions in cDNA-transfected COS-7 cells and dominantly with the particulate fraction in the brain. After Triton X-100 extraction, this isozyme remained in the detergent-insoluble cytoskeletal fraction of the brain and transfected COS-7 cells.
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