Evidence map›Paper›PMID 7862130›Full record

ArticleMolecular and cellular biology1995

A plant mitochondrial sequence transcribed in transgenic tobacco chloroplasts is not edited.

C A Sutton, O V Zoubenko, M R Hanson, P Maliga

Open access · bronzeAbstract read
In one paragraph

Article in Molecular and cellular biology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. When you can't trust the DNA: RNA editing changes transcript sequences.Cellular and molecular life sciences : CMLS · 2011
    Review
  3. Article
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  11. Review
  12. RNA editing in plant organelles: a fertile field.Proceedings of the National Academy of Sciences of the United States of America · 1996
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

C A SuttonSection of Genetics and Development, Cornell University, Ithaca, New York 14853.
O V Zoubenko
M R Hanson
P Maliga
Cornell University · USRutgers, The State University of New Jersey · US

Funding

RNA EDITING IN PLANT ORGANELLESR01GM050723 · NIGMS · CORNELL UNIVERSITY ITHACA · PI HANSON, MAUREEN R · 1994 to 2001
$587k
NIGMS NIH HHS R01GM50723
6 · The paper itself

Abstract

RNA editing occurs in two higher-plant organelles, chloroplasts and mitochondria. Because chloroplasts and mitochondria exhibit some similarity in editing site selection, we investigated whether mitochondrial RNA sequences could be edited in chloroplasts. We produced transgenic tobacco plants that contained chimeric genes in which the second exon of a Petunia hybrida mitochondrial coxII gene was under the control of chloroplast gene regulatory sequences. coxII transcripts accumulated to low or high levels in transgenic chloroplasts containing chimeric genes with the plastid ribosomal protein gene rps16 or the rRNA operon promoter, respectively. Exon 2 of coxII was chosen because it carries seven editing sites and is edited in petunia mitochondria even when located in an abnormal context in an aberrant recombined gene. When editing of the coxII transcripts in transgenic chloroplasts was examined, no RNA editing at any of the usual sites was detected, nor was there any novel editing at any other sites. These results indicate that the RNA editing mechanisms of chloroplasts and mitochondria are not identical but must have at least some organelle-specific components.

Indexed as

Transcription, GeneticAmino Acid SequenceBase SequenceChloroplastsCloning, MolecularDNA, MitochondrialDNA, PlantDNA PrimersElectron Transport Complex IVExonsGenes, PlantMitochondriaMolecular Sequence DataNicotianaPlant LeavesPlantsDNA, MitochondrialDNA, PlantDNA PrimersElectron Transport Complex IV

Identifiers

PMID7862130
PMCPMC230361
OpenAlexW2115990746

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.