ArticleProceedings of the National Academy of Sciences of the United States of America1996
A gene encoding a mitogen-activated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase by touch, cold, and water stress in Arabidopsis thaliana.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers, 1 of them a synthesis that pooled it.
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Who cites it
128 citing papers in PubMed, 1 synthesis or guideline pooled it, 491 citations in OpenAlex.
- Comparative transcriptome meta-analysis of Arabidopsis thaliana under drought and cold stress.PloS one · 2018Pooled it
- Response of Plants to Touch Stress at Morphological, Physiological and Molecular Levels.International journal of molecular sciences · 2025Review
- Integrated transcriptome and proteome analysis reveals molecular responses of soybean anther under high-temperature stress.Frontiers in plant science · 2023Article
- Transcriptome and Physiological Analyses of a Navel Orange Mutant with Improved Drought Tolerance and Water Use Efficiency Caused by Increases of Cuticular Wax Accumulation and ROS Scavenging Capacity.International journal of molecular sciences · 2022Article
- Combined physiological and transcriptome analysis revealed the response mechanism ofFrontiers in plant science · 2022Article
- Integrated physiological and transcriptomic analyses reveal the molecular mechanism behind the response to cultivation inFrontiers in plant science · 2022Article
- Transcriptome Differences in Response Mechanisms to Low-Nitrogen Stress in Two Wheat Varieties.International journal of molecular sciences · 2021Article
- Genome-Wide Identification and Analysis ofInternational journal of molecular sciences · 2021Article
- Expanding the Toolkit of Fluorescent Biosensors for Studying Mitogen Activated Protein Kinases in Plants.International journal of molecular sciences · 2020Article
- Review
- Article
- Survey of Sensitivity to Fatty Acid-Amino Acid Conjugates in the Solanaceae.Journal of chemical ecology · 2020Article
- Biological impacts of phosphomimic AtMYB75.Planta · 2020Article
- De novo Comparative Transcriptome Analysis of Genes Differentially Expressed in the Scion of Homografted and Heterografted Tomato Seedlings.Scientific reports · 2019Article
- Identification of Genes Differentially Expressed in Response to Cold inPlants (Basel, Switzerland) · 2019Article
- Comparative Transcriptomic Analysis of Biological Process and Key Pathway in Three Cotton (International journal of molecular sciences · 2019Article
- Analysis of wheat gene expression related to the oxidative stress response and signal transduction under short-term osmotic stress.Scientific reports · 2019Article
- Identification and Characterization of Mitogen-Activated Protein Kinase (MAPK) Genes in Sunflower (Plants (Basel, Switzerland) · 2019Article
- New functions of an old kinase MPK4 in guard cells.Plant signaling & behavior · 2018Article
- Divergence in the transcriptional landscape between low temperature and freeze shock in cultivated grapevine (Horticulture research · 2018Article
68 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe here the cloning and characterization of a cDNA encoding a protein kinase that has high sequence homology to members of the mitogen-activated protein kinase (MAPK) kinase kinase (MAPKKK or MEKK) family; this cDNA is named cATMEKKI (Arabidopsis thaliana MAP kinase or ERK kinase kinase 1). The catalytic domain of the putative ATMEKK1 protein shows approximately 40% identity with the amino acid sequences of the catalytic domains of MAPKKKs (such as Byr2 from Schizosaccharomyces pombe, Ste11 from Saccharomyces cerevisiae, Bck1 from S. cerevisiae, MEKK from mouse, and NPK1 from tobacco). In yeast cells that overexpress ATMEKK1, the protein kinase replaces Ste11 in responding to mating pheromone. In this study, the expression of three protein kinases was examined by Northern blot analyses: ATMEKK1 (structurally related to MAPKKK), ATMPK3 (structurally related to MAPK), and ATPK19 (structurally related to ribosomal S6 kinase). The mRNA levels of these three protein kinases increased markedly and simultaneously in response to touch, cold, and salinity stress. These results suggest that MAP kinase cascades, which are thought to respond to a variety of extracellular signals, are regulated not only at the posttranslational level but also at the transcriptional level in plants and that MAP kinase cascades in plants may function in transducing signals in the presence of environmental stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.