ArticleMolecular and cellular biology1996
Protein polymorphism generated by differential RNA editing of a plant mitochondrial rps12 gene.
Article in Molecular and cellular biology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 52 citations in OpenAlex.
- Disturbed RNA editing in MORF3-deficient Arabidopsis mitochondria leads to impaired assembly of complex I.Plant physiology · 2025Article
- Deep proteomics reveals incorporation of unedited proteins into mitochondrial protein complexes in Arabidopsis.Plant physiology · 2024Article
- The translational landscape of Arabidopsis mitochondria.Nucleic acids research · 2018Article
- Dynamics of Chloroplast Translation during Chloroplast Differentiation in Maize.PLoS genetics · 2016Article
- RNA Editing in Chloroplasts of Spirodela polyrhiza, an Aquatic Monocotelydonous Species.PloS one · 2015Article
- Natural variation in Arabidopsis leads to the identification of REME1, a pentatricopeptide repeat-DYW protein controlling the editing of mitochondrial transcripts.Plant physiology · 2010Article
- RNA editing: only eleven sites are present in the Physcomitrella patens mitochondrial transcriptome and a universal nomenclature proposal.Molecular genetics and genomics : MGG · 2009Article
- Coordination of gene expression between organellar and nuclear genomes.Nature reviews. Genetics · 2008Review
- Coordination of nuclear and mitochondrial genome expression during mitochondrial biogenesis in Arabidopsis.The Plant cell · 2005Article
- Interactions of mitochondrial and nuclear genes that affect male gametophyte development.The Plant cell · 2004Review
- Surprising features of plastid ndhD transcripts: addition of non-encoded nucleotides and polysome association of mRNAs with an unedited start codon.Nucleic acids research · 2004Article
- Developmental co-variation of RNA editing extent of plastid editing sites exhibiting similar cis-elements.Nucleic acids research · 2003Article
- Transcript abundance supercedes editing efficiency as a factor in developmental variation of chloroplast gene expression.RNA (New York, N.Y.) · 2002Article
- Higher plant mitochondriaThe Plant cell · 1999Article
- A cytoplasmic male sterility-associated mitochondrial peptide in common bean is post-translationally regulated.The Plant cell · 1998Article
- Cell type-specific loss of atp6 RNA editing in cytoplasmic male sterile Sorghum bicolor.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The rps12 gene transcripts encoding mitochondrial ribosomal protein S12 are partially edited in petunia mitochondria. Different petunia lines were found vary in the extent of rps12 transcript editing. To test whether multiple forms of RPS12 proteins are produced in petunia mitochondria as a result of partial editing, we probed mitochondrial proteins with specific antibodies against edited and unedited forms of a 13-amino-acid RPS12 peptide spanning two amino acids affected by RNA editing. Both antibodies reacted with mitochondrial proteins at the expected size for RPS12 proteins. The amounts of unedited RPS12 protein in different petunia lines correlate with the abundance of unedited transcripts in these plants. Unedited rps12 translation products are also detected in other plant species, indicating that polymorphism in mitochondrial rps12 expression is widespread. Moreover, we show that RPS12 proteins recognized by both edited-specific and unedited-specific antibodies are present in a petunia mitochondrial ribosome fraction. These results demonstrate that partially edited transcripts can be translated and that the protein product can accumulate to detectable levels. Therefore, genes exhibiting incompletely edited transcripts can encode more than one gene product in plant mitochondria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.