ArticleJournal of virology1996
Directional budding of human immunodeficiency virus from monocytes.
Article in Journal of virology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 49 citations in OpenAlex.
- Ezrin is a component of the HIV-1 virological presynapse and contributes to the inhibition of cell-cell fusion.Journal of virology · 2014Article
- ROCK1 and LIM kinase modulate retrovirus particle release and cell-cell transmission events.Journal of virology · 2014Article
- The regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapse.PLoS pathogens · 2011Article
- How HIV-1 takes advantage of the cytoskeleton during replication and cell-to-cell transmission.Viruses · 2011Review
- Filamin A protein interacts with human immunodeficiency virus type 1 Gag protein and contributes to productive particle assembly.The Journal of biological chemistry · 2011Article
- Nucleocapsid promotes localization of HIV-1 gag to uropods that participate in virological synapses between T cells.PLoS pathogens · 2010Article
- HIV-1 Virological Synapse: Live Imaging of Transmission.Viruses · 2010Article
- T cell polarization at the virological synapse.Viruses · 2010Article
- Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses.Journal of virology · 2007Article
- HIV-1-infected blood mononuclear cells form an integrin- and agrin-dependent viral synapse to induce efficient HIV-1 transcytosis across epithelial cell monolayer.Molecular biology of the cell · 2005Article
- Functional domains within the human immunodeficiency virus type 2 envelope protein required to enhance virus production.Journal of virology · 2005Article
- Atomic force microscopy investigation of human immunodeficiency virus (HIV) and HIV-infected lymphocytes.Journal of virology · 2003Article
- Directed egress of animal viruses promotes cell-to-cell spread.Journal of virology · 2002Review
- Membrane targeting properties of a herpesvirus tegument protein-retrovirus Gag chimera.Journal of virology · 2000Article
- The double-stranded RNA-binding protein Staufen is incorporated in human immunodeficiency virus type 1: evidence for a role in genomic RNA encapsidation.Journal of virology · 2000Article
- Polarized human immunodeficiency virus budding in lymphocytes involves a tyrosine-based signal and favors cell-to-cell viral transmission.Journal of virology · 1999Article
- Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.Journal of virology · 1999Article
- Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.The Journal of experimental medicine · 1998Article
- Role of actin microfilaments in Black Creek Canal virus morphogenesis.Journal of virology · 1998Article
- Contribution of virion ICAM-1 to human immunodeficiency virus infectivity and sensitivity to neutralization.Journal of virology · 1997Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Time-lapse cinematography revealed that activated human immunodeficiency virus (HIV)-infected monocytes crawl along surfaces, putting forward a leading pseudopod. Scanning electron micrographs showed monocyte pseudopods associated with spherical structures the size of HIV virions, and transmission electron micrographs revealed HIV virions budding from pseudopods. Filamentous actin (F-actin) was localized by electron microscopy in the pseudopod by heavy meromyosin decoration. Colocalization of F-actin and p24 viral antigen by light microscopy immunofluorescence indicated that F-actin and virus were present on the same pseudopod. These observations indicate that monocytes produce virus from a leading pseudopod. We suggest that HIV secretion at the leading edges of donor monocytes/macrophages may be an efficient way for HIV to infect target cells.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.