Trial reportThe American journal of cardiology1997
Intravascular ultrasound analysis of reduction in progression of coronary narrowing by treatment with pravastatin.
Trial report in The American journal of cardiology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01200056 (A Prospective, Double-blinded, Randomised Study to Evaluate the Effects of Different Doses of Statin Treatment on Plaque Volume and Composition in Coronary Disease Determined by Virtual Histology Using Intravascular Ultrasound), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective, Double-blinded, Randomised Study to Evaluate the Effects of Different Doses of Statin Treatment on Plaque Volume and Composition in Coronary Disease Determined by Virtual Histology Using Intravascular Ultrasound
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.
- Effects of statins on progression of coronary artery disease as measured by intravascular ultrasound.Journal of clinical hypertension (Greenwich, Conn.) · 2011Pooled it
- Intracoronary Imaging for the Management of Vulnerable Plaques.Journal of clinical medicine · 2026Review
- Prognostic Role and Therapeutic Implications of Intravascular Optical Coherence Tomography Detected Coronary Plaque Microstructures in Patients with Coronary Artery Disease.Journal of clinical medicine · 2025Review
- Lipid-lowering Therapy and Coronary Plaque Regression.Journal of atherosclerosis and thrombosis · 2024Review
- Reversal of Atherosclerotic Plaque Growth and Vulnerability: Effects of Lipid-Modifying and Anti-Inflammatory Therapeutic Agents.Biomedicines · 2024Review
- Drug intervention as an emerging concept for secondary prevention in patients with coronary disease.Cardiovascular intervention and therapeutics · 2024Review
- Role of Lipid-Lowering and Anti-Inflammatory Therapies on Plaque Stabilization.Journal of clinical medicine · 2024Review
- Effects of Lipid Lowering Therapies on Vulnerable Plaque Features: An Updated Narrative Review of the Literature.Journal of cardiovascular development and disease · 2023Review
- Intra-coronary Imaging for the Evaluation of Plaque Modifications Induced by Drug Therapies for Secondary Prevention.Current atherosclerosis reports · 2020Review
- Teaching Old Treatments New Tricks.Circulation. Cardiovascular interventions · 2020Article
- The Goal of Achieving Atherosclerotic Plaque Regression with Lipid-Lowering Therapy: Insights from IVUS Trials.Journal of atherosclerosis and thrombosis · 2019Review
- Benefit-risk assessment of rosuvastatin in the treatment of atherosclerosis and related diseases.Drug safety · 2014Review
- Systematic study of the effects of lowering low-density lipoprotein-cholesterol on regression of coronary atherosclerotic plaques using intravascular ultrasound.BMC cardiovascular disorders · 2014Review
- Observation of short-term atorvastatin-induced changes in coronary arterial plaque properties using integrated backscatter intravascular ultrasound in a patient.Journal of cardiology cases · 2011Article
- Assessment of coronary plaque progression in coronary computed tomography angiography using a semiquantitative score.JACC. Cardiovascular imaging · 2009Article
- Reproducibility of intravascular ultrasound radiofrequency data analysis: implications for the design of longitudinal studies.The international journal of cardiovascular imaging · 2006Article
- Dedicated calibration formulas permit correction of differences between measurements by different IVUS devices as demonstrated in atherosclerotic human coronary arteries in vitro.The international journal of cardiovascular imaging · 2006Article
- Intravascular ultrasound assessment of atherosclerosis.Current atherosclerosis reports · 2004Review
- Coronary arterial remodeling: from bench to bedside.Current atherosclerosis reports · 2003Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Serial intravascular ultrasound studies were performed to evaluate the effect of pravastatin on coronary atherosclerotic plaque. Administration of pravastatin reduced serum lipid levels and progression of coronary artery atherosclerotic plaque.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.