Evidence map›Paper›PMID 9618731›Full record

ReviewPharmacy world & science : PWS1998

Should we aim at tissue renin-angiotensin systems?

J F Smits, R C Passier, M J Daemen

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in Pharmacy world & science : PWS, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J F SmitsDepartment of Pharmacology, Cardiovascular Research Institute Maastricht (CARIM), Universiteit Maastricht, The Netherlands.
R C Passier
M J Daemen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent developments in our knowledge of the renin-angiotensin system (RAS) necessitate an update of the classical view on this system. These developments pertain to the pathways leading to formation of angiotensin II and other active metabolites, their receptors, biological functions and the presence of renin-angiotensin systems in tissues. The implications of the above new developments for the current interest in tissue renin-angiotensin systems as potential targets for drug therapy in cardiovascular disease are discussed in this review.

Indexed as

Angiotensin-Converting Enzyme InhibitorsAngiotensin IIAnimalsCardiovascular DiseasesGene Expression Regulation, EnzymologicHumansPeptidyl-Dipeptidase APolymorphism, GeneticReceptors, AngiotensinRenin-Angiotensin SystemAngiotensin-Converting Enzyme InhibitorsAngiotensin IIPeptidyl-Dipeptidase AReceptors, Angiotensin

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.