Diet, exercise & lifestyle × glycemic control

TrialJAMA2008

Lifestyle intervention and metformin for treatment of antipsychotic-induced weight gain: a randomized controlled trial.

Ren-Rong Wu et al.PubMed ↗Publisher ↗

What the trial testedrandomised · 128 people · 2008

Randomised comparison

Probably lowered glycemic control

−1.20−1.50 to −0.90

As reported

difference −1.20, 95% CI −1.50 to −0.90

Randomised comparison

Probably lowered glycemic control

−0.50−0.80 to −0.30

As reported

difference −0.50, 95% CI −0.80 to −0.30

Randomised comparison

Probably raised glycemic control

+1.20+0.90 to +1.50

As reported

difference 1.2, 95% CI 0.90–1.50

Three numbers in the abstract

the abstract, start to end

group had mean decreases in BMI of 1.2 (95% CI, 0.9-1.5), insulin

group had mean decreases in BMI of 0.5 (95% CI, 0.3-0.8) and insulin

group had mean increases in BMI of 1.2 (95% CI, 0.9-1.5), insulin

← favours treatmentfavours comparator →
could be chance
Glycemic control
−1.20−1.50 to −0.90
Glycemic control
−0.50−0.80 to −0.30
Glycemic control
1.20.90–1.50
MetforminInsulinDiet, exercise & lifestyleGlycemic control

Insulin × glycemic controlhelps?mixed

unlikelylikely
0.500.50 without it
← favours treatmentfavours comparator →
this papermore certainless certain
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2 trials

Full record →Abstract, authors, funding and every citing paper · PMID 18182600