DPP-4 inhibitors × body weight & composition

TrialDiabetes, obesity & metabolism2008

Efficacy and safety of sitagliptin when added to ongoing metformin therapy in patients with type 2 diabetes.

R Scott et al.PubMed ↗Publisher ↗

What the trial testedrandomised · 273 people · 2008

Randomised comparison

Probably raised body weight & composition

+1.90kg+1.30 to +2.50

As reported

difference 1.9 kg, 95% CI 1.30–2.50

One number in the abstract

the abstract, start to end

sitagliptin and rosiglitazone groups was 1.9 kg (95% CI: 1.3-2.5).

← favours treatmentfavours comparator →
could be chance
Body weight & composition
1.91.30–2.50
DPP-4 inhibitorsThiazolidinedionesBody weight & composition

DPP-4 inhibitors × body weight & compositionhelps?mixed

unlikelylikely
0.500.50 without it

Thiazolidinediones × body weight & compositionhelps?mixed

unlikelylikely
0.00only evidence
← favours treatmentfavours comparator →
this papermore certainless certain
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Full record →Abstract, authors, funding and every citing paper · PMID 18201203