Evidence map›Paper›PMID 18777487›Full record

ArticleDiabetes & vascular disease research2008

Metformin: a multitasking medication.

Cliff J Bailey

Registry-linked trialAbstract readEditorial
PubMed Publisher
In one paragraph

Article in Diabetes & vascular disease research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01881828 (A Randomized Trial of Metformin as Adjunct Therapy for Overweight Adolescents With Type 1 Diabetes), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01881828 phase3completedstarted 2013, after this paper: background citation

A Randomized Trial of Metformin as Adjunct Therapy for Overweight Adolescents With Type 1 Diabetes

Ran2013Enrolled164Registered outcomes16Posted comparisons0ConditionsType 1 DiabetesArmsMetformin (glucophage), oral placebo
PMID 22540912PMID 15855566PMID 12502670PMID 23175691PMID 19996308PMID 20393934PMID 18721166PMID 12107742PMID 12702748PMID 12716791PMID 14514347PMID 14514594other papers from this trial
Open the trial in the graph
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. AMPK: a cellular metabolic and redox sensor. A minireview.Frontiers in bioscience (Landmark edition) · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Cliff J Bailey

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, OralBlood GlucoseCardiovascular AgentsCardiovascular DiseasesDiabetes Mellitus, Type 2HumansHypoglycemic AgentsMetforminTreatment OutcomeBlood GlucoseCardiovascular AgentsHypoglycemic AgentsMetformin

Identifiers

PMID18777487

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.