Statins × inflammation & biomarkers

TrialInternational journal of obesity (2005)2009

Leptin, but not adiponectin, is a predictor of recurrent cardiovascular events in men: results from the LIPID study.

S Söderberg et al.PubMed ↗Publisher ↗

  • Pravastatinlooks bad hereHigher leptin levels, no range given.No ranges given.

What the trial testedas reported · 184 people · 2009

No range given

Reported higher leptin levels, no range given

+6.00percentage points

pravastatin vs placebo

As reported

difference 6 %, no interval

Who was studied, and how

184people with cardiovascular disease, in this paper

The trial randomly assignedassigned by chance

pravastatin
placebo

Reported higher leptin levels, no range given+6.00

randomised

the abstract, start to end

randomly allocated to pravastatin had 6% lower leptin levels (P=0.04)

← favours treatmentfavours comparator →
could be chance
No interval given · direction only, strength unknown
Leptin levelspravastatin vs placebo
6
StatinsInflammation & biomarkers

Statins × inflammation & biomarkershelps?mixed

unlikelylikely
0.480.50 without it
← favours treatmentfavours comparator →
this papermore certainless certain
1 / 6

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Full record →Abstract, authors, funding and every citing paper · PMID 19050671