Who was studied, and how
One number in the abstract
Where each one falls
Where it lands on the map
What it changes
Among 21 other studies
648people in the Multicenter Randomized Controlled Trial of Loading Dose Statins for the Prevention of Cardiovascular Complications in High-Risk Non-Cardiac Surgery trial, from 2012
250of them with cardiovascular disease, in this paper
The trial randomly assignedassigned by chance
fluvastatin
placebo
Probably reduced deaths from cardiovascular causes or myocardial infarction−53%
randomisedthe abstract, start to end
… in the placebo group (hazard ratio, 0.47; 95% CI, 0.24 to 0.94; P=0.03).
← favours treatmentfavours comparator →
could be chanceDeath from cardiovascular causes or myocardial infarctionfluvastatin vs placebo
HR 0.470.24–0.94
StatinsCardiovascular events
Statins × cardiovascular eventshelps?replicated
unlikelylikely
0.860.85 without it
← favours treatmentfavours comparator →
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