ArticleBiochimica et biophysica acta1979
Interaction of plasma lipoproteins with erythrocytes. I. Alteration of erythrocyte morphology.
Article in Biochimica et biophysica acta, 1979. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01634906 (Erythrocyte-bound Apolipoprotein B After Withdrawal of Statin Therapy), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Erythrocyte-bound Apolipoprotein B After Withdrawal of Statin Therapy
Who cites it
10 citing papers in PubMed, 45 citations in OpenAlex.
- Dose-dependent effects of fenugreek seed extract on the biochemical and haematological parameters in high-fat diet-fed rats.Journal of Taibah University Medical Sciences · 2019Article
- A single high-fat meal provokes pathological erythrocyte remodeling and increases myeloperoxidase levels: implications for acute coronary syndrome.Laboratory investigation; a journal of technical methods and pathology · 2018Article
- Red Blood Cell Dysfunction Induced by High-Fat Diet: Potential Implications for Obesity-Related Atherosclerosis.Circulation · 2015Article
- Erythrocyte-bound apolipoprotein B in relation to atherosclerosis, serum lipids and ABO blood group.PloS one · 2013Article
- Haemorheological variables in a rat model of hypertriglyceridaemic obesity and diabetes.Veterinary research communications · 2002Article
- Correction of erythrocyte shape abnormalities in familial hypercholesterolemia after LDL-apheresis: does it influence cerebral hemodynamics?Heart and vessels · 1997Article
- Erythrocyte echinocytosis in liver disease. Role of abnormal plasma high density lipoproteins.The Journal of clinical investigation · 1985Article
- Article
- Phosphatidylinositol turnover in mitogen-activated lymphocytes. Suppression by low-density lipoproteins.The Biochemical journal · 1980Article
- Inhibition of Ca2+ accumulation in mitogen-activated lymphocytes: role of membrane-bound plasma lipoproteins.Proceedings of the National Academy of Sciences of the United States of America · 1980Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intact erythrocytes incubated in the presence of low density lipoproteins (LDL) undergo a time-dependent morphologic transformation from biconcave discs to spherocytes within 4 h. No shape change is observed when erythrocytes are incubated with high density lipoproteins (HDL). The LDL-induced change in erythrocyte morphology occurs without concomitant leakage of hemoglobin from the cell or depletion of intracellular ATP; no change in the distribution of the major lipids of the erythrocyte membranes was detected. The alteration of morphology does require attachment of LDL to the erythrocyte surface. The LDL-induced morphologic alteration is inhibited by HDL, but not by serum albumin. HDL prevent the attachment of LDL to the cell membrane; however, the HDL subfractions, HDL2 and HDL3, are only partially effective. These data suggest that normal erythrocyte morphology and cell function may depend on the concentration and composition of the circulating lipoproteins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.