← Cardiac procedures & devices × cardiovascular events

SynthesisThe Cochrane database of systematic reviews2011

Statins for the primary prevention of cardiovascular disease.

Fiona Taylor et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 34,272 people · 2011

Not counted

Reduced deaths

−17%−27% to −5%

Bigger than 5 in 10 for all-cause mortality

As reported

RR 0.83, 95% CI 0.73–0.95 · the paper's word: All-cause mortality

Not counted

Reduced deaths

−30%−39% to −21%

Bigger than 8 in 10 for all-cause mortality

As reported

RR 0.70, 95% CI 0.61–0.79 · the paper's word: All-cause mortality

Not counted

Reduced cardiovascular events

−34%−47% to −17%

Bigger than 8 in 10 for cardiovascular events

As reported

RR 0.66, 95% CI 0.53–0.83

Three numbers in the abstract

the abstract, start to end

… mortality was reduced by statins (RR 0.83, 95% CI 0.73 to 0.95) as was combined fatal and non-fatal CVD endpoints (RR 0.70, 95% CI 0.61 to 0.79).

… reduction of revascularisation rates (RR 0.66, 95% CI 0.53 to 0.83).

← favours treatmentfavours comparator →
could be chance
All-cause mortality
RR 0.830.73–0.95
All-cause mortality
RR 0.700.61–0.79
Cardiovascular events
RR 0.660.53–0.83
StatinsCardiac procedures & devicesCardiovascular eventsAll-cause mortality
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4 trials

NCT0163490655 enrolled2012NCT02255682phase 435 enrolled2015NCT02796378phase 430 enrolled2016NCT0225067775 enrolled2014
Full record →Abstract, authors, funding and every citing paper · PMID 21249663